Publications by authors named "Ai-Bing Xu"
Article Synopsis
- The study investigates the impact of cancer cachexia in patients with hepatocellular carcinoma (HCC), focusing on how body composition changes over time can help identify cachexia.
- It utilizes a cohort of unresectable HCC patients treated with specific therapies, analyzing body composition through CT scans to categorize patients into different cachexia phases based on their skeletal muscle mass and total adipose tissue.
- Findings reveal that patients experiencing significant declines in muscle and tissue mass have worse overall survival outcomes, highlighting the importance of monitoring body composition in HCC treatment plans.
Article Synopsis
Article Synopsis
- This study evaluates the combined effectiveness of transarterial chemoembolization (TACE) with PD-(L)1 inhibitors and molecular targeted treatments (MTT) compared to TACE alone in treating hepatocellular carcinoma (HCC).
- It involved 826 patients, with 376 receiving the combination treatment and 450 undergoing TACE monotherapy, and measured outcomes like progression-free survival (PFS) and overall survival (OS).
- Findings indicated that the combination treatment significantly improved PFS (9.5 months vs. 8.0 months) and OS (19.2 months vs. 15.7 months) while maintaining a manageable safety profile, especially in patients with advanced HCC.
Leucine aminopeptidases (LAPs) were associated with tumor cell proliferation, invasion and/or angiogenesis. LAP3 is one important member of this family. However, its clinical significance and biological function in hepatocellular carcinoma (HCC) remains unknown.
View Article and Find Full Text PDFObjective: To explore the clinical therapeutic efficacies of combined three-dimensional conformal radiotherapy (3DCRT) plus transcatheter arterial chemoembolization (TACE) for portal vein tumor thrombus (PVTT) in hepatocellular carcinoma (HCC).
Methods: A total of 145 HCC patients with tumor thrombus in portal vein were divided randomly into 2 groups. Group A (n = 64) was treated with surgical intervention alone while group B (n = 81) underwent 3DCRT plus TACE.