Publications by authors named "Ai-Bin Cheng"
Background/aims: Erinacine, which is extracted from the medicinal mushroom Hericium erinaceus, is known to play anticancer roles in human cancers. The following study aims to investigate the role of erinacine in the opening of the mitochondrial permeability transition pore (MPTP) in hepatocellular carcinoma (HCC) through the PI3K/Akt/GSK-3β signaling pathway and highlights the applicability of erinacine in HCC treatments.
Methods: HCC and paracancerous tissues were obtained from 85 HCC patients who've undergone surgical resection.
Objective: The aim of this study is to investigate the clinical effect of goal-directed fluid therapy in elderly patients with radical resection of bladder cancer.
Materials And Methods: Seventy-six elderly patients with radical resection of bladder cancer were selected from October 2012 to October 2014 and randomly divided into two groups, in which 38 patients received routine treatment as the control group and 38 patients received goal-directed fluid therapy based on routine treatment as the observation group. The treatment effect was compared between two groups.
Article Synopsis
- This meta-analysis aimed to investigate how diabetes mellitus (DM) affects the recovery of patients who have suffered an ischemic stroke by reviewing various studies on this topic.
- After screening through 253 studies, 13 case-control studies involving 8,463 patients were included in the analysis, focusing on those with DM and ischemic stroke.
- The findings revealed that while blood glucose levels significantly differed between patients with DM and those without after 48 hours post-stroke, other important recovery indicators such as treatment effectiveness, fatality rates, and NIHSS scores showed no significant differences between the two patient groups.
We aim to investigate the effects of sevoflurane on the ATPase activity of the hippocampal neurons in rats with cerebral ischemia-reperfusion injury (IRI) via the cyclic adenosine monophosphate (cAMP) and protein kinase A (PKA) signaling pathway. Sixty rats were assigned into the normal, model and sevoflurane groups (n = 20, the latter two groups were established as focal cerebral IRI models). The ATPase activity was detected using an ultramicro Na (+)-K (+)-ATP enzyme kit.
View Article and Find Full Text PDFCarnosol protects against spinal cord injury through Nrf-2 upregulation.
J Recept Signal Transduct Res
October 2016
Background: Carnosol is an ortho-diphenolic diterpene with excellent antioxidant potential. The present study was designed to identify the protective role of carnosol against spinal cord injury (SCI)-induced oxidative stress and inflammation in Wistar rats.
Methods: In the present study, oxidative stress status was determined through estimating total antioxidant capacity, total oxidant status, lipid peroxide content, protein carbonyl and sulfhydryl levels, reactive oxygen species (ROS), antioxidant status (superoxide-dismutase, catalase, glutathione, glutathione peroxidase, glutathione-S-transferase).
[The distribution of angiotensin converting enzyme gene I/D polymorphism and its relationship with essential hypertension].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
October 2003
Objective: To observe the distribution character of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism in Chinese population and its relationship with essential hypertension.
Methods: Polymerase chain reaction (PCR) technique was used to detect the angiotensin converting enzyme gene I/D polymorphism in 2966 subjects of Kailuan Coal Mine, and further restriction analysis was performed.
Results: The frequencies of ACE II, ID, DD genotypes in total study population were 41.