Synopsis of recent research by authors named "Ai Thu Bui"
Recent research by Ai Thu Bui focuses on the molecular mechanisms underlying dental enamel formation and the impact of environmental toxicants on oral health, utilizing innovative animal models and methods to explore these phenomena.!
A significant finding highlights the role of amelogenin phosphorylation in enamel integrity, showing that disruption of this process leads to severe enamel defects and pathological changes in ameloblasts, as demonstrated in a knock-in mouse model.!
Additionally, Bui's investigations emphasize the oral cavity as a critical site for assessing environmental exposure and its implications for developmental dental defects, underscoring the need for reliable markers of exposure to endocrine disruptors during enamel formation.!