Publications by authors named "Ai Mieda"
Article Synopsis
- The study introduces a 3D model called 'axioloid' derived from pluripotent stem cells that accurately mimics human somitogenesis, overcoming limitations faced in traditional models.
- Axioloids exhibit key features such as the proper patterning of segments and crucial signaling gradients, particularly highlighting the role of retinoic acid in segment stabilization.
- This model shows potential for understanding human congenital spine diseases, providing a valuable tool for future research on axial development and related disorders.
