Publications by authors named "Ai Lin Tai"
Heart failure, a major public health issue, often stems from prolonged stress or damage to the heart muscle, leading to cardiac hypertrophy. This can progress to heart failure and other cardiovascular problems. Doxorubicin (DOX), a common chemotherapy drug, and isoproterenol (ISO), a β-adrenergic agonist, both induce cardiac hypertrophy through different mechanisms.
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- Diabetic cardiovascular dysfunction is a serious complication of type 2 diabetes, driven by inflammation and myocardial fibrosis, leading to heart structure and function issues.
- A study compared different mouse groups, including those with type 2 diabetes, and found that blackcurrant extract (Bla.C) improved blood sugar levels and heart function, reducing biomarkers for fibrosis and inflammation.
- The findings suggest that Bla.C may help prevent cardiovascular complications in diabetes by addressing inflammation and improving overall heart health, highlighting its potential therapeutic value.
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- Renal ischemia-reperfusion (I/R) injury is a significant cause of acute renal failure, and the study investigates the effects of Geumgwe-sinkihwan (GSH), a traditional Chinese medicine, on a mouse model of this condition.
- The experiment involved administering different doses of GSH to mice after inducing I/R injury through surgical clamping of renal arteries, revealing that GSH improves kidney function and reduces markers of renal injury.
- The results showed that GSH decreases inflammatory cytokines and inflammasome-related proteins, suggesting its potential as a therapeutic agent to mitigate renal damage and inflammation in cases of acute renal failure.
Background: Acute postoperative pain (APOP) may cause complications and delay healing. Analgesics alone cannot completely relieve APOP. Preoperative anxiety, optimism, and pain catastrophizing are predictors of APOP.
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