Publications by authors named "Ahmetagic S"
Article Synopsis
- The study focuses on the prevalence of antibiotic resistance in Brucella melitensis strains isolated from patients in Bosnia and Herzegovina, highlighting significant human health concerns due to brucellosis.
- Among the 108 strains analyzed, a notable 84.3% showed resistance to trimethoprim-sulfamethoxazole in standard broth, while over 90% were resistant to azithromycin in multiple testing environments.
- The findings suggest that alternative testing methods, like enriched broth, may improve understanding of antimicrobial resistance, indicating a need for further genomic studies to investigate the underlying mechanisms of resistance in these bacteria.
Article Synopsis
- The study investigates COVID-19 transmission within Bosnian households, highlighting that the virus spreads through contact, droplets, and air, particularly in multi-generational family settings.
- Conducted between March and December 2020, the research analyzed 25 index cases, all middle-aged men, leading to a significant 61.8% secondary transmission rate among 123 family members.
- The findings reveal high intrafamilial transmission in Bosnia and Herzegovina, emphasizing the importance of preventive measures due to the serious impact, including hospitalizations and deaths.
Article Synopsis
- Cytomegalovirus (CMV) is a common infection that affects people of all ages, with serious implications for newborns when contracted during pregnancy.
- The study aimed to assess the incidence of CMV infection among pregnant women in Tuzla Canton and identify risk factors related to the infection.
- Results showed a high rate of IgG antibodies (93%) in the studied population, with a statistically significant link between living in rural areas and lower education levels as risk factors for CMV infection.
Article Synopsis
- Chronic HCV infection primarily affects intravenous drug users (IVDU), with a high prevalence rate of 40%-90%, leading to an 80% risk of developing chronic infection.
- The study aimed to compare clinical characteristics and treatment outcomes of chronic HCV between IVDU and non-user populations and to analyze the efficacy of treatment in Tuzla Canton.
- Results showed a predominance of younger males in the IVDU group, along with notable differences in laboratory values and genotype frequencies, suggesting variations in disease progression and treatment response.
The burden and epidemiology of community-acquired central nervous system infections: a multinational study.
Eur J Clin Microbiol Infect Dis
September 2017
Risk assessment of central nervous system (CNS) infection patients is of key importance in predicting likely pathogens. However, data are lacking on the epidemiology globally. We performed a multicenter study to understand the burden of community-acquired CNS (CA-CNS) infections between 2012 and 2014.
View Article and Find Full Text PDFA measles outbreak with two epidemic waves involving 4649 probable and laboratory-confirmed cases was recorded in six out of ten cantons of the Federation of Bosnia and Herzegovina between February 2014 and April 2015. The majority of the patients had never received measles vaccination (3115/4649, 67.00%), and the vaccination status of another 23% was unknown (1066/4649).
View Article and Find Full Text PDFAim: To analyse clinical, laboratory and epidemiological characteristics of brucellosis in children in Bosnia and Herzegovina.
Methods: The study included 246 children aged 0-18 years, who were hospitalized in Clinics and Departments for Infectious Diseases in Tuzla, Sarajevo, Banja Luka, Zenica and Bihać in the period 2000-2013, in whom the diagnosis of brucellosis was established based on anamnestic data, clinical features and positive results from blood culture and/or positive results from one of the serological tests.
Results: In this period, a total of 2630 patients, 246 (9.
Objective: The use of commercially available noninvasive markers for chronic hepatitis B (CHB) related fibrosis is not widely available in developing countries so clinicians in those countries frequently use free alternatives. We aimed to create an optimized algorithm for selection of patients with the highest probability for presence/absence of significant liver fibrosis and cirrhosis based on the use of multiple free scores.
Methods: We evaluated six free noninvasive markers for CHB related fibrosis against liver biopsy and selected the best thresholds for prediction/exclusion of significant fibrosis and cirrhosis in CHB patients.
Article Synopsis
- More than 30 years after AIDS was recognized, the study analyzes the epidemiological and clinical characteristics of 28 HIV-infected patients treated at a clinic in Tuzla from 1996 to 2013.
- The majority of patients were male (82.14%), with a significant number infected through heterosexual contact, and nearly 57% showed no symptoms of infection at their first visit.
- The study found a notable occurrence of opportunistic diseases, especially tuberculosis, and revealed a death rate of 21.4% among the patients.
Acute respiratory distress syndrome (ARDS) is a form of acute life threatening respiratory failure. In daily practice there is difficulty in diagnostic and therapeutic management of Acute respiratory distress syndrome (ARDS). We observed delay in diagnostic and therapeutic procedures in patients with clinical signs for the presence of severe respiratory disorders.
View Article and Find Full Text PDFArticle Synopsis
- Between January 2014 and February 2015, Bosnia and Herzegovina reported 3,804 measles cases, primarily in Bugojno, Fojnica, and Travnik.
- Around 70% of these cases were unvaccinated, and 20% had unknown vaccination status.
- Health authorities are actively checking vaccination records and implementing prevention measures, but the epidemic continues.
Aim: To describe the first two cases of West Nile virus (WNV) neuroinvasive infections in Bosnia and Herzegovina.
Methods: At the Clinic for Infectious Diseases of the University Clinical Centre Tuzla, Bosnia and Herzegovina (BiH), specific screening for WNV infection was performed on patients with neuroinvasive diseases from 1 August to 31 October 2013. Serum samples were tested for the presence of WNV IgM and IgG antibodies using enzyme-linked immunosorbent assay (ELISA); positive serum samples were further analyzed by detection of WNV nucleic acid of two distinct lineages (lineage 1 and lineage 2) in sera by RT-PCR.
Article Synopsis
- Acinetobacter baumannii is a major cause of difficult-to-treat nosocomial infections in hospitals, particularly in intensive care units.
- The study tracked 855 patients in a clinic, finding that 12.3% developed infections, with A. baumannii causing 51.4% of these cases, primarily respiratory infections.
- Most A. baumannii isolates showed resistance to multiple antibiotics, though many were susceptible to tobramycin and all to colistin, highlighting the need for improved antibiotic strategies and infection control measures.
Article Synopsis
- ICUs have a higher risk of nosocomial infections (NIs), prompting a study to evaluate the rates, locations, and bacteria involved at a surgical ICU in Tuzla.
- In 2010, 11.27% of the 834 studied patients developed NIs, with respiratory and urinary tract infections being the most common.
- Gram-negative bacteria, especially Klebsiella pneumoniae, were predominant, highlighting the need for ongoing infection control in ICU settings.
Aim: To determine the etiology of peritonitis, as well as the sensitivity of isolated bacteria to antibiotics.
Methods: Study was performed at the Surgical Clinic, Department of Anesthesiology and Reanimation, Department of Microbiology, Department of Clinical Pharmacology of University Clinical Centre (UCC) Tuzla. In a prospective study, starting from 1.
Article Synopsis
- The study compared ICU features, antimicrobial resistance patterns, infection control policies, and disease distribution across 88 ICUs in central Europe to Mid-West Asia.
- Out of 749 patients assessed, pneumonia was the most common infection, with significant occurrences of hospital-acquired infections and a notable prevalence of multidrug-resistant pathogens like Enteric Gram-negatives and Acinetobacter spp.
- Surveillance and management practices showed variability, with Turkey conducting more infection surveillance than Iran and Southeastern Europe, while Southeastern Europe had higher adherence to culture-guided antibiotic treatment.
Introduction: Hospital-acquired Urinary tract infections make 35% of all the hospital-acquired infections, and about 80% of them are related to the catheterization of the urinary bladder.
Purpose: To determine clinical characteristics and dominant etiologic factors of Urinary Tract Infections associated with urinary catheter (C-UTIs).
Methods: Determined clinical characteristics of C-UTIs were prospectively analyzed on 38 hospitalized patients in the Clinic for Infectious Diseases at the University Clinical Centre Tuzla, from January 1(st) 2011 to December 31(st) 2011.
Introduction: Clostridium difficile (C. difficile) is currently the leading cause of healthcare-associated diarrhea, but almost nothing is known about the extent of C. difficile infection (CDI) in Bosnia and Herzegovina.
View Article and Find Full Text PDFConflict Of Interest: none declared.
Goal: The goal of the research is to determine the relationship between frequency and reporting of stab incidents, attitudes and knowledge about stab incidents and occupational risk for transmission of viral infection with HBV, HCV or HIV among health care professionals employed in primary health care.
Material And Methods: Conducted is prospective, cross-section study by questionnaires in 2012.
Aim: To determine a predictive potential of biochemical and clinical parameters, including independent predictors of the therapeutic outcome in patients with H1N1 influenza.
Methods: In this retrospective study, 119 patients treated at the Clinic for Infectious Diseases in Tuzla in the period July 2009 to February 2010 were included. They were at the age of 1 month up to 80 years.
Article Synopsis
- Bacterial meningitis is a serious infectious disease in children, and this study focused on identifying its common causes in Tuzla Canton.
- A retrospective analysis of 140 children aged 1 month to 14 years revealed a prevalence of 1.53/1000, with most cases occurring in younger children and primarily during the spring months.
- The leading pathogens identified were Haemophilus influenzae, Neisseria meningitides, and Streptococcus pneumoniae, with a low mortality rate of 2.14%.
Introduction: The prevalence of human brucellosis in Bosnia and Herzegovina and the Tuzla Canton reached its peak in 2008, with a reported total of 994 cases within country, and with 104 cases within the Tuzla Canton.
Aim: to analyze the clinical and epidemiological features of human brucellosis in patients hospitalized at the University Clinical Center Tuzla during the period from 01/01/2000 till the 31/12/2010.
Methods: We retrospectively analyzed the clinical symptoms, the laboratory and X-ray findings, the treatments, and the course and outcome of the disease.
Association of Gastroenterologists and Hepatologists of Bosnia and Herzegovina based on the experiences of domestic and foreign centers operating in the field of hepatology and accepted guidelines of the European and the U.S. Association for Liver Diseases adopted the consensus for the diagnosis and treatment of chronic viral hepatitis B and C.
View Article and Find Full Text PDFThe 4th Congress of Infectiologists of Bosnia-Herzegovina with international participation was held in Konjic, on 30. May to 02. June 2012.
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