Publications by authors named "Ahmet Cagdas-Yumurtas"

Objective: Despite significant advances in understanding hypertrophic cardiomyopathy (HCM) in recent years, there is a need to improve risk stratification for patients at high risk of adverse outcomes. The relationship between inflammation and disease severity in HCM patients is known. Recently, a new inflammation parameter called the pan-immune inflammation value (PIV) has been introduced.

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Systemic immune-inflammation index (SII) is obtained by multiplying the platelets by the ratio of neutrophils to lymphocytes. We aimed to examine the relationship between contrast induced nephropathy (CIN) development and SII in non-ST-segment elevation myocardial infarction (NSTEMI) patients. 1124 NSTEMI patients included and divided into two groups according to the development of CIN.

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Article Synopsis
  • Atrial fibrillation (AF) is often triggered by atrial premature complexes (APCs) during exercise, and this study aims to understand their relationship through long-term patient follow-up.
  • The research involved 1559 patients without obstructive coronary artery disease, divided into AF (+) and AF (-) groups based on the development of AF over an average follow-up of around 48 months.
  • Findings indicate that older age and the presence of APCs during exercise significantly increase the risk of developing AF, with patients showing APCs having a much lower AF-free survival rate.
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Background: Atrial flutter (AFL) and atrial fibrillation (AF) are the most commonly detected supraventricular arrhythmias and share similar pathophysiological mechanisms. After the successful ablation of AFL, AF frequently occurs in the long-term follow-up. As emphasized in some studies, certain mechanisms seem to predispose to the development of AF in AFL patients, and approximately 20% of these patients have accompanying AFL.

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There is a lack of data about the association between admission serum albumin levels and long-term mortality in heart failure (HF) patients with cardiac resynchronization therapy defibrillators (CRT-D). We aim to investigate this connection in HF patients with CRT-D. The study population consisted of 477 HF patients with CRT-D.

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Background: The ratio of pulmonary artery diameter (PAD) to ascending aortic diameter (AoD) has been reported to be a prognostic marker in several lung diseases; however, the usefulness of this tool in patients with acute pulmonary embolism (APE) is unknown. Here, we aimed to determine the long-term prognostic value of the PAD/AoD ratio in patients with APE.

Methods: A total of 275 patients diagnosed with APE at our tertiary care center between November 2016 and February 2022 were included in the study.

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Background: The treadmill exercise test is widely used to determine cardiovascular risk and mortality. Premature ventricular complexes (PVCs) are frequently observed during exercise stress testing. The literature on the role of PVCs observed during treadmill exercise testing in predicting prognosis is controversial.

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Background: The hypertrophic cardiomyopathy (HCM) risk- sudden cardiac death (SCD) model provides a convenient tool for determining the risk of SCD in patients with HCM even though some patients with low-risk scores still remain at risk of SCD. Hence, the aim of our study was to assess the performance of HCM Risk-SCD in a large series of consecutive patients with HCM who had been followed up in a tertiary center.

Methods: The study population consisted of 389 consecutive HCM patients who had been followed up between 2004 and 2021.

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Background/introduction: Heart failure patients with reduced ejection fraction are at high risk for ventricular arrhythmias and sudden cardiac death. Ivabradine, a specific inhibitor of the If current in the sinoatrial node, provides heart rate reduction in sinus rhythm and angina control in chronic coronary syndromes.

Objective: The effect of ivabradine on ventricular arrhythmias in heart failure patients with reduced ejection fraction patients has not been fully elucidated.

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Article Synopsis
  • The study explores how obesity, measured by body fat percentage (BFP) and relative fat mass (RFM), impacts outcomes in patients with non-ST-segment elevation myocardial infarction (NSTEMI), noting an "obesity paradox" where obese patients seem to have better prognoses despite having CAD.
  • A total of 748 NSTEMI patients were analyzed, revealing that obese individuals had similar peak creatine kinase-MB (CK-MB) levels compared to non-obese patients, but displayed better cardiac function and less severe coronary artery disease upon evaluation.
  • Key findings suggest that higher BFP correlates with smaller infarct size, indicating that certain measures of obesity might have beneficial effects on heart health outcomes during NSTEM
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Background And Objectives: The morphology-voltage-P-wave duration (MVP) electrocardiography (ECG) risk score is a newly defined scoring system that has recently been used for atrial fibrillation (AF) prediction. The aim of this study was to evaluate the ability of the MVP ECG risk score to predict AF in patients with an implantable cardioverter defibrillator (ICD) and heart failure with reduced ejection fraction in long-term follow-up.

Methods: The study used a single-center, and retrospective design.

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The Naples score is a new prognostic score developed according to inflammatory and nutritional status and frequently evaluated in cancer patients. The present study aimed to evaluate using the Naples prognostic score (NPS) to predict the development of decreased left ventricular ejection fraction (LVEF) after acute ST-segment elevation myocardial infarction (STEMI). The study has a multicenter and retrospective design and included 2280 patients with STEMI who underwent primary percutaneous coronary intervention (pPCI) between 2017 and 2022.

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Background: Over the past few years, smartwatches have become increasingly popular in the monitoring of arrhythmias. Although the detection of atrial fibrillation with smartwatches has been the subject of various articles, there is no comprehensive research on the detection of arrhythmias other than atrial fibrillation. In this study, we included individual cases from the literature to identify the characteristics of patients with smartwatch-detected arrhythmias other than atrial fibrillation.

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Background: There is a lack of current research examining the predictive value of the Intermountain Risk Score (IMRS) in patients with ST-segment elevation myocardial infarction (STEMI) caused by cardiogenic shock. Therefore, the purpose of this research was to investigate the ability of IMRS to predict short- and long-term mortality in patients with cardiogenic shock triggered by STEMI.

Methods: The participants included 492 consecutive cardiogenic shock patients who underwent primary percutaneous coronary intervention following STEMI.

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In this study, we aimed to determine whether body mass index (BMI) is an independent predictor of in-hospital mortality in ST-segment elevation myocardial infarction (STEMI) patients and to assess the relationship between BMI and mortality. One thousand three hundred fifty-seven patients with STEMI were included to the study. Primary outcome was in-hospital mortality.

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Article Synopsis
  • Implantable cardioverter defibrillators (ICDs) are used in patients with heart failure with reduced ejection fraction (HFrEF) to help prevent arrhythmic deaths.
  • A study analyzed data from 1107 patients who received ICDs at a hospital between 2009 and 2019, finding a one-year mortality rate of 4.7%.
  • Key risk factors for mortality within one year included age, presence of atrial fibrillation, New York Heart Association classification greater than 2, blood urea nitrogen levels, pro-brain natriuretic peptide, and albumin levels.
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Background: Pro-inflammatory pathways play an important role in the follow-ups of patients with intracardiac defibrillators (ICDs) for heart failure (HF) reduced with ejection fraction (HFrEF). A newly defined index - the systemic immune-inflammation index (SII)-has recently been reported to have prognostic value in patients with cardiovascular disease. This study's aim is to evaluate the SII value regarding its association with long-term mortality and appropriate ICD therapy during a 10-year follow-up.

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Background: This investigation aimed to examine and compare the predictive value of MADIT-II, FADES, PACE and SHOCKED scores in predicting one-year and long-term all-cause mortality in implantable cardioverter-defibrillator (ICD) implanted patients, 75 years old and older, since there has been an area of uncertainty about the utility and usefulness of these available risk scores in such cases.

Methods: In this observational, retrospective study, 189 ICD implanted geriatric patients were divided into two groups according to the presence of long-term mortality in follow-up. The baseline characteristics and laboratory variables were compared between the groups.

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Background: High-intensity statin (HIS) therapy is widely recommended for secondary prevention after an acute myocardial infarction (AMI). The 2019 European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) dyslipidemia guidelines have lowered the target low-density lipoprotein cholesterol (LDL-C) level, which necessitates a more frequent use of nonstatin therapies.

Objectives: The objectives of the study were to investigate the rate of LDL-C target attainment for secondary prevention in AMI patients.

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Background: Patients with heart failure with reduced ejection fraction (HFrEF) who received implantable cardiac defibrillator (ICD) still remain at high risk due to pump failure and prevalent comorbid conditions. The primary aim of this research was to evaluate the predictive value of C-reactive protein-to-albumin ratio (CAR) for all-cause mortality among patients with HFrEF despite ICD implantation.

Materials And Methods: Those who were implanted ICD for HFrEF in our institution between 2009 and 2019 were included.

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Background: The benefit of implantable cardiac defibrillator (ICD) in patients with heart failure and reduced ejection fraction (HFrEF) could be limited in a particular group of patients. Low prognostic nutritional index (PNI) indicates malnutrition and proinflammatory condition. We sought to investigate the value of PNI in predicting long-term mortality among HFrEF patients with ICD.

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