Antimicrobial Peptides From Different Sources: Isolation, Purification, and Characterization to Potential Applications.

Antimicrobial peptides (AMPs) are excellent promising candidates for biomedical applications owing to their structural properties, high biocompatibility, good biodegradability, and functional diversity. Unlike conventional antibiotics, AMPs have been shown to have broad-spectrum antimicrobial activity toward Gram-positive/negative bacteria, as well as antifungal and antiviral activity. These peptides have also been found to be cytotoxic to sperm and cancer cells.

Exploring the microplastic pollution: Unveiling origins and varieties in coastal sediments and waters of the Bushehr Province, Persian Gulf, Iran.

In this study, microplastic (MP) pollution in the coastal sediments and tidal waters of Bushehr province in the Persian Gulf was comprehensively investigated. The sampling stations were selected based on their proximity to various human activities in January and February 2022, such as tourism, fishing, urban development and industry. The results showed that the abundance of MP associated with different human activities varied.

Ivabradine effects in hospitalized acute heart failure patients: a single center retrospective study.

Background: An increased heart rate (HR) is deleterious in patients with decompensated heart failure. Ivabradine, an HR lowering agent which acts by inhibiting the I current in the sinoatrial node, is indicated for chronic heart failure with reduced ejection fraction. However, data regarding the safety and efficacy of ivabradine in acute decompensated heart failure is limited.

Synthesis of core-shell material rich in carboxyl groups and its application in the selective adsorption of cationic peptides.

The ability to extract peptides and proteins from biological samples with excellent reusability, high adsorption capacity, and great selectivity is essential in scientific research and medical applications. Inspired by the advantages of core-shell materials, we fabricated a core-shell material using amino-functionalized silica as the core. Benzene-1,3,5-tricarbaldehyde and 3,5-diaminobenzoic acid were used as model organic ligands to construct a shell coating by alternately reacting the two monomers on the surface of silica microspheres.