Association of Polymorphisms with Allergic Rhinitis in Jordanian Population.

Allergic rhinitis has complex patterns of inheritance, and single nucleotide polymorphisms, a common genetic variation in a population, exert a significant role in allergic rhinitis pathology. The current study aimed to investigate the association of polymorphisms with allergic rhinitis. Our study included 158 patients with allergic rhinitis and 140 healthy controls from Jordan that were genotyped for single nucleotide polymorphisms (SNPs) C-589T (rs2243250) and T-2979G (rs2227284) using restriction fragment length polymorphism-polymerase chain reaction.