Preparation and characterization of bioactive polyvinylpyrrolidone film via electrospinning technique.

Electrospinning technique became a very common and effective method to fabricate nonwoven films with a large surface area for different purposes especially in the biomedical field. Antimicrobial submicron fibrous films based on polyvinylpyrrolidone (PVP) doped with silver nanoparticles (Ag-NPs), Zinc Oxide (ZnO), and (Ag-NPS/ZnO), were successfully fabricated via the electrospinning technique. The morphology and the elemental configurations of the as-prepared films were studied by using scanning electron microscope with EDX.

Preparation and Biological Activity of New Collagen Composites, Part I: Collagen/Zinc Titanate Nanocomposites.

The aim of this investigation was to develop new antimicrobial collagen/zinc titanate (ZnTiO3) biomaterials using a sol-gel cryogenic draying technology in keeping the native collagen activity. Broad-spectrum antimicrobial activity was demonstrated against Firmicutes (Staphylococcus epidermidis, Bacillus cereus, and Candida lusitaniae) and Gracilicutes (Escherichia coli, Salmonella enterica, and Pseudomonas putida) microorganisms. The antimicrobial activity as well as the cytotoxicity were specific for the different test microorganisms (Gram-positive and Gram-negative bacteria and fungi) and model eukaryotic cells (osteosarcoma, fibroblast, and keratinocyte cells), respectively, and both were depending on the ZnTiO3 concentration.