Publications by authors named "Ahmed Ramiz Baykan"

Article Synopsis
  • Intestinal metaplasia (IM) and Helicobacter pylori (HP) are identified as risk factors for developing gastric cancer (GC), with the WNT signaling pathway playing a significant role in this transition.
  • A study involving 104 patients analyzed the expression of WNT pathway-related genes in those with GC, IM, and control groups using advanced PCR methods.
  • Results showed that the genes RHOA, CSNK1A1, DVL2, FZD8, and LRP5 were overexpressed in GC and IM patients, particularly in those with metastasis or HP positivity, indicating these genes might serve as poor prognosis biomarkers for gastric cancer.
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Objective: Coronavirus disease-2019 (COVID-19) disease can cause asymptomatic and mild flu-like symptoms as well as severe symptoms ranging from respiratory failure and death. Growth hormone (GH) is produced in the anterior pituitary and plays an important role in the immune system. COVID-19 is severe in the elderly, men, obese, diabetics, and people with immune deficiency.

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Background and objective Pediatric guidelines on the diagnosis of celiac disease (CD) have reported that the positivity of anti-endomysium antibodies in the presence of anti-transglutaminase antibodies (TGA) 10 times higher than normal is sufficient for the diagnosis. In this study, we aimed to evaluate whether this diagnostic process for children can also be applied to adult patients. Materials and methods We retrospectively examined patients aged >18 years who were diagnosed with CD.

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Objective: At present, there is no reliable indicator for dietary compliance and disease severity in patients with celiac disease (CD). The aim of this study is to evaluate mean platelet volume (MPV) level as a biomarker for detection of disease activation, dietary adherence, and assessment of disease severity.

Methods: Eighty-one patients with CD and 50 healthy subjects were enrolled in this study.

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Objectives: To evaluate the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) in elderly patients (≥85 years old).

Material And Methods: Patients who underwent ERCP for any reason within 12 months were evaluated. Patients undergoing ERCP were classified as the elderly group aged 85 years and older or the controls under the age of 85 years.

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Article Synopsis
  • - This study evaluated the role of galectin-3, a biochemical marker, in predicting pneumonia severity in COVID-19 patients, suggesting that higher levels indicate worse lung involvement.
  • - Researchers analyzed 176 confirmed COVID-19 patients, finding those with typical pneumonia had significantly higher galectin-3 levels compared to those with atypical or no pneumonia.
  • - A specific cut-off level for galectin-3 (18.9 ng/mL) was identified as a strong indicator for diagnosing typical pneumonia in COVID-19, with notable sensitivity and specificity.
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Background/aims: Atrophic gastritis (AG), intestinal metaplasia (IM), and Helicobacter pylori (HP) are the risk factors for the development of gastric cancer (GC). Chromatin remodeling is one of the epigenetic mechanisms involved in the carcinogenesis of GC. The purpose of this study was to investigate the expression profiles of defined chromatin remodeling genes in gastric mucosal samples and their values as gastric carcinogenesis biomarkers.

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Klinefelter syndrome (KS) is a chromosomal abnormality characterised by a 47, XXY karyotype associated with hypogonadism and infertility. We present a case of a 20-year-old patient who applied to our clinic because of growth deficiency and was concurrently diagnosed with Klinefelter syndrome and celiac disease.

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