Tramadol-associated seizures in Egypt: Epidemiological, clinical, and radiological study.

Background: Tramadol intake related seizures have emerged as a common cause of seizures in Egypt affecting mainly young men.

Objective: This study aimed to determine the percentage of tramadol induced seizures, and to compare the clinical, neurophysiological, and radiological features of tramadol induced seizures group with idiopathic epilepsy group.

Methods: Two phases study; at first phase, data analysis for all Kasr-Alainy epilepsy clinic patients in Cairo during the period from January 2012 through June 2014, then at second phase a group of tramadol induced seizures' patients were compared with a matching group of idiopathic epilepsy patients.