Efficacy of Intralesional Antigen Versus Measles, Mumps, and Rubella Vaccine Versus Topical Podophyllin in Treatment of Resistant Genital Warts.

Background: No single treatment is ideal for genital warts with high rate of resistance using conventional modalities as topical podophyllin; however, several intralesional immunotherapies are being tested nowadays, with variable results. In this study, we compared the safety and efficacy of treating resistant and recurrent genital warts by 2 intralesional immunotherapies [ antigen and measles, mumps, and rubella (MMR) vaccine] and compared them with topical podophyllin.

Patients/methods: A total of 45 patients with resistant or recurrent genital warts were enrolled in this study.