Efficacy and safety of perioperative ketamine for the prevention of chronic postsurgical pain: A meta-analysis.

Study Objective: Assessment of the efficacy and safety of perioperative intravenous ketamine in reducing incidence and severity of chronic postsurgical pain.

Study Design: A systematic review and meta-analysis of randomized controlled trials (RCTs).

Data Sources: The following data sources were systematically searched: MEDLINE, CENTRAL, and EMBASE (till 02/2021).