The effect of the combined application of repetitive transcranial magnetic stimulation and local injection of botulinum neurotoxin versus their individual use in children with spastic diplegic cerebral palsy.

Background: Botulinum neurotoxin (BoNT) is frequently utilized for localized spasticity in patients with spastic diplegic cerebral palsy (CP), while repetitive transcranial magnetic stimulation (rTMS) offers a potential therapeutic option.

Objective: To assess and compare BoNT and rTMS effects among children with spastic diplegic CP on spasticity and motor function. Additionally, investigate the potential advantages of combining these therapeutic modalities.