Publications by authors named "Ahmed Fawzy Selim"
Article Synopsis
- Valproic acid (VPA) is a widely used drug for epilepsy but can lead to liver damage with long-term use.
- Liraglutide, an antidiabetic medication with anti-inflammatory properties, was tested for its potential to protect the liver from damage caused by VPA in a study involving rats.
- Results showed that liraglutide effectively reduced liver enzyme levels and markers of oxidative stress and inflammation, suggesting it can help mitigate VPA-induced liver damage.
Purpose: The aim of the present work was to investigate whether hepatitis C virus treatment by directly acting antivirals obligate shifting patients with type 2 diabetes from oral hypoglycemic drugs to insulin therapy.
Methods: This was a prospective study including 92 treatment-naïve patients with chronic hepatitis C virus infection and type 2 diabetes who were eligible for treatment with directly acting antivirals (sofosbuvir + daclatasvir ± ribavirin). Patients in the study were divided into two groups; group 1 included 22 patients on insulin therapy and group 2 included 70 patients on oral antidiabetic medications.