Stratified analyses of genome wide association study data reveal haplotypes for a candidate gene on chromosome 2 (KIAA1211L) is associated with opioid use in patients of Arabian descent.

Background: Genome Wide Association Studies (GWAS) have been conducted to identify genes and pathways involved in development of opioid use disorder. This study extends the first GWAS of substance use disorder (SUD) patients from the United Arab Emirates (UAE) by stratifying the study group based on opioid use, which is the most common substance of use in this cohort.

Methods: The GWAS cohort consisted of 512 (262 case, 250 controls) male participants from the UAE.

A case-control genome wide association study of substance use disorder (SUD) identifies novel variants on chromosome 7p14.1 in patients from the United Arab Emirates (UAE).

Genome wide association studies (GWASs) have provided insights into the molecular basis of the disorder in different population. This study presents the first GWAS of substance use disorder (SUD) in patients from the United Arab Emirates (UAE). The aim was to identify genetic association(s) that may provide insights into the molecular basis of the disorder.

The frequency of rs1076560 and rs1799971 in substance use disorder patients from the United Arab Emirates.

Background: Dopaminergic and opioid systems are involved in mediating drug reward and reinforcement of various types of substances including psychoactive compounds. Genes of both systems have been candidate for investigation for associations with substance use disorder (SUD) in various populations. This study is the first study to determine the allele frequency and the genetic association of the rs1076560 SNP and rs1799971 SNP variants in clinically diagnosed patients with SUD from the United Arab Emirates (UAE).

Physicians' experiences of SBIRT training and implementation for SUD management in primary care in the UAE: a qualitative study.

Unlabelled: AimThe objective of this paper is to present a qualitative study of introducing substance misuse screening using the Screening Brief Intervention and Referral to Treatment (SBIRT) model, in primary care in Abu Dhabi.

Background: Substance misuse in the UAE is an increasing problem. However religious beliefs and fear of legal consequences have prevented this topic from being openly discussed, risk levels identified through screening and treatment options offered.

The pattern of substance use disorder in the United Arab Emirates in 2015: results of a National Rehabilitation Centre cohort study.

Background: Substance use disorder (SUD) is a global problem with no boundaries, which also afflicts individuals from countries of the Arabian Peninsula. Data from this region is limited. In an effort to develop targeted prevention and intervention initiatives in the United Arab Emirates (UAE), it was necessary to identify the nature of substance use by describing the characteristics of those using different substances.

Energy drinks in the Gulf Cooperation Council states: A review.

Energy drinks have become a popular beverage worldwide. This review was carried out to have an overview among adolescents and emerging adults in the Gulf Co-operation Council states about energy drinks consumption rates and other related issues such as starting age and patterns of energy drink consumption. The Medline and Embase databases were searched separately using different terms such as energy drinks, energy beverages, and caffeinated drinks.

Adolescents' perception of substance use and factors influencing its use: a qualitative study in Abu Dhabi.

Objective: The objective of this article is to gain a deeper understanding of the attitudes and perceptions of adolescents in the United Arab Emirates regarding substance and to identify factors that, in their view, may influence the risk of substance use and suggest possible interventions.

Design: This was a qualitative study that used a focus group approach.

Setting: The study was carried out in Abu Dhabi, United Arab Emirates.