Valvular involvement in granulomatosis with polyangiitis: Case report and systematic review of literature.

Background: Granulomatosis with polyangiitis (GPA) is a systemic inflammatory condition; however, patients with GPA rarely experience endocardial valve lesions.

Methods: We report a GPA case with tricuspid valve destruction together with a systematic review to highlight the characteristics of all previously reported GPA cases with valvular involvement.

Results: Among 36 cases included, the aortic valve was involved in 15 (41.