Publications by authors named "Ahmed Abu Zaid"
Smell and taste sensations have been linked to positive outcomes in the feeding of premature infants, though the impact on the time required to transition to oral feeding remains unclear. This study aimed to evaluate the beneficial effects of smell and taste interventions on clinical outcomes in preterm infants. We conducted a search in PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials from inception through September 2024 for randomized controlled trials (RCTs) examining the effects of smell and taste on clinical outcomes in preterm infants with a gestational age of less than 34 weeks.
View Article and Find Full Text PDFObjective: To conduct a systematic review and network meta-analysis to evaluate the safety and efficacy of intrapolyp steroid injection compared with oral steroids, nasal steroid wash, nasal steroid spray, and a control group in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).
Data Sources: PubMed, Scopus, Web of Science, Embase, and CENTRAL.
Review Methods: Both randomized and non-randomized clinical trials were included.
: Cerebral palsy (CP) constitutes a group of enduring movement disorders arising from non-progressive brain damage, often accompanied by epilepsy. This study aims to explore the prevalence of epilepsy in CP patients, dissecting demographic characteristics, healthcare parameters, and nuanced risk factors. : The study employed the National Inpatient Sample (NIS) database (2016-2019, four years).
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- The study conducted a meta-analysis to assess the effectiveness and safety of tranexamic acid (TXA) during endoscopic sinus surgery by analyzing data from 23 randomized controlled trials involving 1,597 patients.
- TXA significantly reduced intraoperative blood loss, decreased operating time, and improved surgical field quality and surgeon satisfaction compared to control groups, with no reported thromboembolic events.
- Despite the positive results, the findings were affected by significant variations in study quality and heterogeneity among the included trials.
Article Synopsis
- This study conducted a meta-analysis of randomized controlled trials comparing preoperative misoprostol to control treatments in women undergoing abdominal myomectomies, covering data from six databases until April 2024.
- It analyzed 16 trials involving 975 women and found many studies had a low quality or biases, but the results indicated that misoprostol significantly reduced intraoperative blood loss, hemoglobin drop, and the need for blood transfusions compared to control.
- Additionally, misoprostol led to shorter operative times and hospital stays, although there was no significant difference in postoperative fever rates between the two groups.
Article Synopsis
- Recent studies highlight a link between vitamin D levels and male reproductive health, particularly how deficiency can lead to infertility.
- A systematic review of randomized controlled trials found that vitamin D supplementation increased total testosterone levels in men but had no significant impact on other reproductive hormone parameters like free testosterone and FSH.
- The analysis suggests that while vitamin D may boost total testosterone, more well-structured studies are necessary to fully understand its effects on other hormones related to male fertility.*
Unlabelled: To assess the effectiveness of glossopharyngeal nerve block (GNB) in the treatment of postoperative pain among patients undergoing tonsillectomy, a systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted. Various databases, including PubMed, Cochrane, Scopus, Web of Science, and Google Scholar, were systematically screened from inception until March 2023. The included studies were assessed using the RoB-2 tool.
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- The study investigates the use of nebulized tranexamic acid (TXA) for treating post-tonsillectomy bleeding (PTB), a common complication leading to emergency department visits.
- By systematically reviewing nine studies, the researchers assessed the effectiveness and safety of nebulized TXA, finding a lower reoperation rate for those treated with TXA compared to those who weren't.
- The results suggest that nebulized TXA is a safe and effective treatment for PTB, but more extensive research is needed to confirm these findings.
Article Synopsis
- Cerebral palsy (CP) significantly raises the risk of developing hip dysplasia (HD), as demonstrated by a study analyzing data from over 3.9 million pediatric patients in a national database from 2016-2019.
- The study found that CP patients have a substantially higher likelihood of having HD, with females and older individuals being at higher risk, and race also playing a role in this association.
- The findings underscore the necessity for additional research to better understand the connection between CP and HD and improve patient care.
: The existing literature lacks conclusive evidence regarding the relationship between bronchopulmonary dysplasia (BPD) and cerebral palsy (CP). This large epidemiological study aimed to explore the co-occurrence of BPD and CP among children. : This retrospective cohort analysis utilized the National Inpatient Sample (NIS) dataset from 2016 to 2019, investigating pediatric patients with BPD and CP diagnoses.
View Article and Find Full Text PDFObjective: Several graft options can be used to construct a neovagina. This study aimed to evaluate the efficacy of creating a neovagina using a fresh human amnion in women with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.
Methods: Ten patients were analyzed retrospectively.
Background And Aim: Conflicting results on the effect of magnesium supplementation on blood pressure have been published in previous meta-analyses; hence, we conducted this umbrella meta-analysis of RCTs to provide a more robust conclusion on its effects.
Methods: Four databases including PubMed, Scopus, EMBASE, and Web of Science were searched to find pertinent papers published on international scientific from inception up to July 15, 2024. We utilized STATA version 17.
Aim: To conduct the first-ever systematic review and meta-analysis evaluating calcium infusion versus cabergoline in preventing ovarian hyperstimulation syndrome (OHSS) among high-risk women undergoing assisted reproductive technology.
Methods: Six databases were screened from inception until April 1, 2024. The included randomized and non-randomized controlled studies were assessed for quality.
Objective: This study aimed to systematically examine the relationship between polycystic ovary syndrome and ovarian, endometrial, and cervical cancers using the National Inpatient Sample (NIS) database.
Methods: We utilized the International Classification of Diseases (ICD-10) system to identify relevant codes from the NIS database (2016-2019). Univariate and multivariable regression analyses (adjusted age, race, hospital region, hospital teaching status, income Zip score, smoking, alcohol use, and hormonal replacement therapy) were conducted to evaluate association between PCOS and gynecologic cancers.
Background: () infection is widely recognized for its association with gastric diseases. Prior studies on the relationship between infection and biliary diseases have faced constraints, including inadequate control of confounding factors and small sample sizes. This study aims to explore the association between infection and biliary diseases using a large, population-based sample with adequate control for various covariates.
View Article and Find Full Text PDFBackground: Laryngeal cancer has a significant impact on speech, swallowing, and quality of life. This study aims to analyze laryngeal cancer trends using the National Inpatient Sample (NIS) database, providing insights into its epidemiology.
Methods: Data from the NIS database was analyzed for a cohort of 14,282 laryngeal cancer cases from 2016 to 2019.
mTOR is a central regulator of cell growth and metabolism in response to mitogenic and nutrient signals. Notably, mTOR is not only found in the cytoplasm but also in the nucleus. This review highlights direct involvement of nuclear mTOR in regulating transcription factors, orchestrating epigenetic modifications, and facilitating chromatin remodeling.
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- - The study explored the relationship between microscopic colitis (MC) and celiac disease (CD) using a large population database from 2016-2019, focusing on patient data analyzed through medical codes.
- - Out of over 26 million patients, 6,836 had MC, with a significant association to CD found in both statistical analyses, indicating that patients with MC are more likely to have CD (OR = 15.71).
- - The presence of CD in patients with MC was linked to higher in-hospital mortality, suggesting CD may act as an independent risk factor for worse outcomes in these patients, highlighting the need for further studies.
Effectiveness of preoperative multimedia educational sessions on the levels of anxiety and satisfaction among women undergoing cesarean: a systematic review and meta-analysis.
Women Health
May 2024
This systematic review and meta-analysis aimed to explore the effectiveness of preoperative multimedia educational sessions on the levels of anxiety and satisfaction among women undergoing cesarean section (CS). The Scopus, PubMed, and Cochrane databases were searched without language limitations for eligible randomized controlled trials (RCTs) published from their inception up to October 15, 2023. A random-effect meta-analysis was conducted, and the quality of this meta-analysis was evaluated using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) approach.
View Article and Find Full Text PDFBackground: We investigated the potential association between Marfan Syndrome (MFS) and adverse obstetric outcomes using the National Inpatient Sample (NIS) database.
Methods: We utilized the International Classification of Diseases (ICD-10) system to identify relevant codes and extracted data from the NIS database covering the period 2016-2019. Descriptive statistics and χ tests were employed to summarize and compare baseline characteristics.
Neuroblastoma with MYCN amplification (MNA) is a high-risk disease that has a poor survival rate. Neuroblastoma displays cellular heterogeneity, including more differentiated (adrenergic) and more primitive (mesenchymal) cellular states. Here, we demonstrate that MYCN oncoprotein promotes a cellular state switch in mesenchymal cells to an adrenergic state, accompanied by induction of histone lysine demethylase 4 family members (KDM4A-C) that act in concert to control the expression of MYCN and adrenergic core regulatory circulatory (CRC) transcription factors.
View Article and Find Full Text PDFBackground: Tutoplast-processed fascia lata (TPFL) is an allograft substance employed alongside cartilaginous materials to achieve optimal augmentation in rhinoplasty. Alternatively, it can be utilized to conceal and smooth irregularities of the nasal dorsum during the procedure. Despite its application, there is limited available data on the extended safety of TPFL.
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- This study aimed to systematically review and analyze randomized controlled trials (RCTs) examining the effectiveness of low-dose aspirin (LDA) in preventing preterm birth (PB).
- The findings showed that LDA significantly reduced the risk of preterm birth before 37 weeks and before 34 weeks, but the evidence was stronger for births before 37 weeks and varied across studies.
- The conclusion suggests that while LDA is beneficial, more high-quality research is needed to clarify the best dosage, timing, and duration of treatment for preventing preterm births across different populations.
Objective: We investigated the potential relationship between endometriosis and risk of ovarian, endometrial, cervical, and breast cancers using the National Inpatient Sample (NIS) database.
Methods: We utilized the International Classification of Diseases (ICD-10) system to identify relevant codes from the NIS database (2016-2019). Univariate and multivariate regression analyses (adjusted for age, race, hospital region, hospital teaching status, income Zip score, smoking, alcohol use, and hormonal replacement therapy) were conducted to evaluate the association between endometriosis and gynecologic cancers and summarized as odds ratios (ORs) with 95% confidence intervals (CIs).