Different Dilutions of Mesobotox in Facial Rejuvenation: Which is Better?

Background: Microbotulinum toxin A treatment is a technique of delivering multiple intradermal injections of diluted botulinum toxin type A into the dermis or the interface between the dermis and the superficial layer of the facial muscles to preserve the facial mobility. The current study aimed to evaluate and compare the clinical effect of different dilutions of microbotulinum toxin A in periorbital and mid-facial rejuvenation.

Methods: This randomized prospective interventional study included 30 female patients with different types of wrinkles in periorbital and/or mid-face.

Fractional CO laser in the treatment of nail psoriasis: how can it help?

Treating nail psoriasis is often a time-consuming challenge with an unsecure outcome. Response to the treatment is variable and relapses are common. Systemic treatments have multiple systemic side effects and lack of the patient compliance makes intra-lesional therapies not the best choice for treatment of nail psoriasis.

Assessment of serum chemerin levels in acanthosis nigricans: A case-control study.

Background: Acanthosis nigricans (AN) is an asymptomatic skin condition linked to several underlying systemic conditions. Chemerin is an adipokine that increases during inflammatory disorders such as metabolic syndrome (MetS).

Aims: This case-control study investigates the link between AN and the underlying MetS and serum levels of chemerin in individuals with obesity.

Superficial Cryotherapy versus Intralesional Corticosteroids Injection in Alopecia Areata: A Trichoscopic Comparative Study.

Background: Alopecia areata (AA) is an autoimmune disease leading to noncicatricial alopecia. Topical or intralesional corticosteroid (ILCS) is the accepted therapeutic option for mild cases; however, adverse effects are sometimes difficult to reverse. When the exposure to liquefied nitrogen is limited to a few seconds "superficial" cryotherapy, reactive vasodilation may improve microcirculation and nutritional status around hair follicles.

Intralesional combined digoxin and furosemide in plantar warts: Does it work?

Background: Warts are small, benign growths caused by human papilloma virus. No treatment has yet proven 100% effective for a cure. DNA viruses rely on K + influx for replication.

Fractional CO2 laser, platelet rich plasma and narrow band ultraviolet B in the treatment of Vitiligo (A randomized clinical trial).

Vitiligo is a chronic acquired disease. Various therapeutic strategies are available but with variable degrees of success. Fractional CO2 laser is claimed to be effective in the treatment of refractory non-segmental vitiligo.

Comparative evaluation of topical diclofenac sodium versus topical ibuprofen in the treatment of seborrheic keratosis.

In 2016, a case of seborrheic keratosis was successfully treated with diclofenac gel 3%. Diclofenac gel mechanism of action is most likely through induction of apoptosis. This study included 30 patients with multiple seborrheic keratosis.

Fractional microneedling radiofrequency in striae alba: Do growth factors add value?

Background: Various treatment modalities have been applied to treat striae alba (SA) with low satisfaction rate. Fractional microneedling radiofrequency (FMR) provides deep dermal coagulation, thereby inducing collagen synthesis and tissue tightening. The addition of platelet-derived lyophilized growth factors may add to the effect of FMR.