Impact of reconstruction algorithms at different sphere-to-background ratios on PET quantification: A phantom study.

Using National Electrical Manufacturers Association (NEMA) phantom, the behavior of four distinct Positron Emission Tomography/Computed Tomography (PET/CT) reconstruction algorithms was investigated. These reconstruction algorithms were (Ordered Subset Expectation Maximization (OSEM), OSEM+ (Point Spread Function) PSF, OSEM + Time of Flight (TOF), and OSEM + TOF + PSF), and the focus was on sphere sizes and SBRs using recovery coefficients as a quantitation method. The obtained results demonstrated the significant effect of TOF on Gibbs artifact and Partial Volume Effect (PVE) at various Sphere-to-Background Ratios (SBRs).

Investigating the Impact of Voxel Size and Postfiltering on Quantitative Analysis of Positron Emission Tomography/Computed Tomography: A Phantom Study.

Aim: This study aims to investigate the influence of voxel size and postfiltering on the quantification of standardized uptake value (SUV) in positron emission tomography/computed tomography (PET/CT) images.

Materials And Methods: National Electrical Manufacturers Association phantom with the spheres of different sizes were utilized to simulate the lesions. The phantom was scanned using a PET/CT scanner, and the acquired images were reconstructed using two different matrix sizes, (192 × 192) and (256 × 256), and a wide range of postfiltering values.