Clinical outcomes, molecular epidemiology and resistance mechanisms of multidrug-resistant isolated from bloodstream infections from Qatar.

Background: Bloodstream infections (BSIs) caused by multidrug-resistant (MDR)- are associated with poor clinical outcomes, at least partly due to delayed appropriate antimicrobial therapy. The characteristics of MDR- bloodstream isolates have not been evaluated in Qatar. Our study aimed to examine susceptibility, clinical and molecular characteristics, and mechanisms of resistance of MDR- bloodstream isolates from Qatar.

Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review.

Immune checkpoint inhibitors (ICIs)-anti-programmed death-1 (PD-1) and their ligands (PD-L1 and PD-L2) have become widely used in the treatment of several malignancies. Many immune-related adverse events (irAEs) have been linked to these agents. Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported.