Comparative study of itraconazole-cyclodextrin inclusion complex and its commercial product.

Itraconazole (ITZ) solid complex using hydroxypropyl-beta-cyclodextrin (ITZ-HP-beta-CD) with 20% polyvinylpyrrolidone was prepared by a co-evaporation method. The complex improved antifungal activity against C. parapasilosis and C.

Investigation of self-microemulsifying and microemulsion systems for protection of prednisolone from gamma radiation.

Radiation is efficient for terminal sterilization. Unfortunately, its use for liquid pharmaceuticals is difficult. This work investigated the potential radioprotective effect of self-microemulsifying (SMEDDS), microemulsions and their phase transition systems which were reported to enhance ocular drug delivery.