Publications by authors named "Ahmed A Al-Saleh"

Background: Late detection of ocular diseases negatively affects patients' quality of life (QoL), encompassing health status, psychological, financial, and social aspects. However, the early detection of eye conditions leads to rapid intervention and avoiding complications, thus preserving the QoL. This study assessed the impact of ocular diseases late detection on patients' QoL at multi-eye clinics based on questionnaire responses.

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Purpose: To measure anterior segment parameters of the eye in myopic Saudi population using Pentacam.

Method: This is retrospective cross-sectional study. Subjects were divided into three groups: low, moderate and high myopia groups.

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Purpose: The aim of this study was to evaluate the effectiveness of occlusion therapy in the control of intermittent exotropia (IXT) in children between 4 and 10 years in Saudi Arabia. This study will highlight the importance of patching IXT patients and assist to approach the proper use of occlusion therapy.

Methods: A clinical, prospective cohort pilot study was performed on 21 untreated IXT patients.

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Purpose: To analyze the post operative results of targeting zero spherical aberration by selecting the best-fit aspheric intraocular lens (IOL), based on preoperative corneal spherical aberration of patients with phacoemulsification surgery.

Setting: AlHokama Eye Specialist Center, Riyadh, Saudi Arabia.

Period: From the 1st of October 2012 until the 10th of April 2013.

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Purpose: To find out the mean corneal spherical aberration and its changes with age in Saudi population.

Setting: AlHokama Eye Specialist Center, Riyadh, Saudi Arabia.

Methods: Three hundred (300) eyes of 185 Saudi subjects (97 men and 88 women), whose age ranged from 15 to 85 years old, with matched refractive errors, were divided into three groups according to their age, 100 for each.

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Purpose: To evaluate compliance of amblyopic patients to patching, and to identify reasons of poor compliance and suggest methods to overcome the problem.

Methods: We conducted a cross-sectional, retrospective study that included 37 families with a child diagnosed with unilateral amblyopia (age range 3-16 years) and attending the Pediatrics Ophthalmology clinic at the King Abdulaziz University Hospital (a tertiary eye hospital). Data were collected through interviews and from hospital charts.

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Myopia is an extremely common eye disorder but the pathogenesis of its isolated form, which accounts for the overwhelming majority of cases, remains poorly understood. There is strong evidence for genetic predisposition to myopia, but determining myopia genetic risk factors has been difficult to achieve. We have identified Mendelian forms of myopia in four consanguineous families and implemented exome/autozygome analysis to identify homozygous truncating variants in LRPAP1 and CTSH as the likely causal mutations.

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To carry out an ophthalmological and detailed genetic investigation on a 7-year-old boy with isolated foveal hypoplasia. A full ophthalmological examination and optical coherence tomography (OCT) was performed. We also performed a full genome screen for chromosomal abnormalities, and searched for mutations in two genes (GPR143 and OCA2) known to be associated with ocular albinism and PAX6 gene known to be associated with aniridia.

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Purpose: To investigate the impact of laser in situ keratomileusis (LASIK) on the change in pupil size immediately after the procedure.

Methods: In a prospective study, measurement of pupil size was assessed in 70 eyes of 35 consecutive patients using a hand-held pupillometer before and immediately after LASIK in mesopic condition at the refractive eye center, Riyadh, Saudi Arabia.

Results: The pupil showed mild dilation immediate after LASIK.

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