Synergetic effects of nano-boehmite and Y nano-zeolite on catalytic cracking of residue oil.

Boehmite nanoparticles and NaY nanozeolite were synthesized by co-precipitation and hydrothermal methods, respectively, and characterized by XRD, FT-IR, TG-DTA, BET, and SEM techniques. XRD and BET analyses demonstrated the formation of boehmite nanoparticles with a surface area of 350 m/g and high crystallinity NaY nanozeolite with a surface area of 957 m/g. In order to evaluate the effect of the content of the mesoporous boehmite nanoparticles on the catalytic performance of the Residue Fluid Catalytic Cracking (RFCC) catalyst, alumina active matrix-based and silica inactive matrix-based catalysts were prepared.

Construction of a cell cycle-specific lncRNA-miRNA-mRNA network reveals novel key lncRNAs in colorectal cancer.

Objective: The current study aimed to determine the roles of pivotal and novel lncRNAs associated with the cell cycle in the occurrence and development of Colorectal cancer (CRC).

Methods: The TCGA-COAD project related to CRC was downloaded, and differential expression analysis was performed to identify differentially expressed lncRNAs, miRNAs, and mRNAs. A cell cycle-associated lncRNA-miRNA-mRNA regulatory network was constructed, and two novel lncRNAs were selected.

Ultrasound-assisted magnetic dispersive micro-solid-phase extraction based on carbon quantum dots/zeolite imidazolate framework-90/polyvinyl pyrrolidone/FeO followed by high-performance liquid chromatography with ultraviolet detection for trace analysis of paracetamol and etodolac in human plasma.

A four-part and sustainable nanocomposite composed of carbon quantum dots modified with zeolite imidazolate framework-90, polyvinyl pyrrolidone and magnetite (CQDs/ZIF-90/PVP/FeO) was fabricated and applied in ultrasound-assisted magnetic dispersive micro-solid-phase extraction (US-A-MDMSPE). US-A-MDMSPE was followed by high-performance liquid chromatography with ultraviolet detection (HPLC-UV) for extraction, enrichment and simultaneous low-level monitoring of paracetamol (PCM) and etodolac (EDL) in human plasma. To increase the extraction yield and improve the sensitivity, nanohybrid arrays of metal-organic frameworks and conductive polymers were immobilized on the surface of CQDs followed by magnetization.

Respiratory failure and rhabdomyolysis caused by severe hypokalemia in a young female with hypertension: a rare critical condition in primary aldosteronism.

Background: The two classic manifestations of primary aldosteronism are hypertension and hypokalemia. However, acute respiratory failure due to hypokalemia in primary hyperaldosteronism is rare.

Case Presentation: The patient was a 27-year-old female who presented with drowsiness and weakness in all extremities.

A systematic review and meta-analysis of functional vitamin B12 status among adult vegans.

The dietary intake of vitamin B12 among unsupplemented vegans is notably lower compared to both vegetarians and omnivores. Prolonged low intakes of vitamin B12, such as seen in those adhering to a vegan diet, lead to physiological deficiency of vitamin B12 and an elevated risk of B12-related morbidity. However, while serum B12 serves as a conventional biomarker for assessing B12 status, its utility is limited given its sensitivity and specificity in ascribing physiological deficiency of B12 and the functional vitamin B12 status of those adhering to vegan diets is unclear.

Identification of key genes and pathways involved in T-DM1-resistance in OE-19 esophageal cancer cells through bioinformatics analysis.

Introduction: Esophageal Cancer (EC) ranks among the most common malignancies worldwide. Most EC patients acquire drug resistance to chemotherapy either intrinsically or acquired after T-DM1 treatment, which shows that increasing or decreasing the expression of particular genes might influence chemotherapeutic sensitivity or resistance. Therefore, gaining a deeper understanding of the altered expression of genes involved in EC drug resistance and developing new therapeutic methods are essential targets for continued advancement in EC therapy.

A comparative assessment of uncrushed-river concrete mix of Hari-River, and Kamar-Kalaq: the two widely used concrete mix in Herat, Afghanistan.

Concrete, as a cornerstone of modern construction, heavily relies on the quality of its constituent materials, particularly aggregates. Among the critical factors contributing to high-quality concrete are proper gradation, absence of clay particles, and angular shape of aggregates. Adhering to these standards typically results in concrete with superior strength.

Comparison of the gene expression profiles of endometrial and trophoblastic cells in women with recurrent miscarriage: A bioinformatics approach.

Background: Recurrent miscarriage (RM) remains unsolved in 50% of patients and causes physical and psychological problems in women without specific risk factors for miscarriage. For a successful pregnancy, acceptance of the endometrium and invasion of trophoblast cells into the endometrium is necessary.

Objective: This study aimed to use computational analysis to identify key genes and related pathways in endometrial and trophoblast cells derived from RM samples.

Assessing the impact of organic and inorganic micropollutants released from a wastewater treatment plant on humans and aquatic environment, Al-Hoceima city, Morocco.

Wastewater contains a variety of compounds qualified as pollutants. These undergo incomplete treatment in wastewater treatment plants. The objective of this study is to determine the potential impacts on humans and aquatic environment of 46 organic and inorganic micropollutants using the USE-tox® model.

Design of multi-epitope vaccine candidate based on OmpA, CarO and ZnuD proteins against multi-drug resistant .

has been identified as a major cause of nosocomial infections. Acinetobacter infections are often difficult to treat with multidrug resistant phenotypes. One of the most effective ways to combat infectious diseases is through vaccination.

A Brief Overview of the Diagnosis and Treatment of Cobalamin (B12) Deficiency.

Background: An increasing number of adult individuals are at risk of vitamin B12 deficiency, either from reduced nutritional intake or impaired gastrointestinal B12 absorption.

Objective: This study aims to review the current best practices for the diagnosis and treatment of individuals with vitamin B12 deficiency.

Methods: A narrative literature review of the diagnosis and treatment of vitamin B12 deficiency.

The importance of heteroresistance and efflux pumps in bedaquiline-resistant Mycobacterium tuberculosis isolates from Iran.

Background: Tuberculosis (TB) continues to pose a threat to communities worldwide and remains a significant public health issue in several countries. We assessed the role of heteroresistance and efflux pumps in bedaquiline (BDQ)-resistant Mycobacterium tuberculosis isolates.

Methods: Nineteen clinical isolates were included in the study, of which fifteen isolates were classified as MDR or XDR, while four isolates were fully susceptible.

Assessing the Effectiveness of Stabilized Cysteamine 5% Cream Compared to Hydroquinone 4%/Ascorbic Acid 3% Combination Cream in Treating Acne-induced Post-inflammatory Hyperpigmentation: A Randomized, Controlled Study.

Objective: Postinflammatory hyperpigmentation (PIH) is a common sequela of acne vulgaris. Topical treatment with hydroquinone is the standard treatment, but may be associated with complications. Cysteamine is a relatively safe depigmenting agent with an observed depigmenting effect.

The Abundance of Plasmid-Mediated Quinolone Resistance Genes in Strains Isolated from Clinical Specimens in Kermanshah, Iran.

Background: () is one of the most common causing nosocomial infections. Plasmid-mediated quinolone resistance (PMQR) determinants have been considered recently. This study evaluated the abundance of PMQR genes in strains of obtained from clinical samples in Kermanshah, Iran.

Potential distribution of Biscogniauxia mediterranea and Obolarina persica causal agents of oak charcoal disease in Iran's Zagros forests.

In Iran, native oak species are under threat from episodes of Charcoal Disease, a decline syndrome driven by abiotic stressors (e.g. drought, elevated temperature) and biotic components, Biscogniauxia mediterranea (De Not.

Fixel-Based Analysis Reveals Tau-Related White Matter Changes in Early Stages of Alzheimer's Disease.

Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD) using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes has been challenging due to the methodological limitations of DTI. We applied fixel-based analyses (FBA) to examine microscopic differences in fiber density (FD) and macroscopic changes in fiber cross-section (FC) in early stages of AD ( = 393, 212 females).

Introduction of protein vaccine candidate based on AP65, AP33, and α-actinin proteins against Trichomonas vaginalis parasite: an immunoinformatics design.

Background: Trichomonas vaginalis is the most common nonviral sexually transmitted disease (STI) worldwide. Vaccination is generally considered to be one of the most effective methods of preventing infectious diseases. Using AP65, AP33 and α-actinin proteins, this research aims to develop a protein vaccine against Trichomonas vaginalis.

The significant improvement in ovarian PCOS syndrome using hydralazine and alendronate aromatase inhibitor FDA-approved drugs in Wistar rat models.

Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility. The aim of this study was to investigate the therapeutic potential of vitamin C, glutamine, mesalazine, hydralazine, and alendronate as new drug candidates for the treatment of letrozole-induced PCOS in female Wistar rats. PCOS was induced in rats by intramuscular injection of estradiol valerate (2 mg/kg body weight for 28 days).

Climatic variables are more effective on the spatial distribution of oak forests than land use change across their historical range.

The current research is conducted to model the effect of climate change and land use change (LUC) on the geographical distribution of Quercus brantii Lindl. (QB) forests across their historical range. Forecasting was done based on six general circulation models under RCP 2.

Bioinformatics analysis of a disease-specific lncRNA-miRNA-mRNA regulatory network in recurrent spontaneous abortion (RSA).

Background: This study investigated the molecular mechanisms of long non-coding RNAs (lncRNAs) in RSA using the lncRNA-miRNA-mRNA regulatory network.

Methods: The present study obtained expression datasets of long non-coding RNAs (lncRNAs), messenger RNAs (mRNAs), and microRNAs (miRNAs) from blood samples of individuals with unexplained recurrent spontaneous abortion (RSA) and healthy controls. Differentially expressed lncRNAs (DELs), mRNAs (DEMs), and miRNAs (DEmiRs) were identified.

EMDR other psychological therapies for PTSD: a systematic review and individual participant data meta-analysis.

Background: This systematic review and individual participant data meta-analysis (IPDMA) examined the overall effectiveness of eye movement desensitization and reprocessing (EMDR) in reducing posttraumatic stress disorder (PTSD) symptoms, achieving response and remission, and reducing treatment dropout among adults with PTSD compared to other psychological treatments. Additionally, we examined available participant-level moderators of the efficacy of EMDR.

Methods: This study included randomized controlled trials.

Preparation of Synbiotic Yogurt Sauce Containing Microalgae Extract and Its Effect on the Viability of .

Background: Preparing a healthy and practical substitute for mayonnaise and reducing the complications caused by its consumption are two of the concerns of the producers of this product. Therefore, this study was conducted with the aim of evaluating the possibility of producing synbiotic yogurt sauce prepared with microalgae extract (SPAE) as a valuable and alternative product for mayonnaise.

Materials And Methods: After preparing yogurt from fresh cow's milk, synbiotic yogurt sauce was prepared according to the formulation, and the effect of SPAE at the rate of 0.

Molecular detection of genes encoding resistance to tetracycline and quinolones among strains isolated from children with acute diarrhea in southwest Iran.

Background And Objectives: An increase in the antibiotic resistance of isolates has caused major global challenges in antimicrobial therapy. Knowledge of local antibiotic resistance trends is essential for selecting appropriate antibiotic treatment regimens. This study aimed to evaluate the frequency of efflux-mediated tetracycline resistance () and plasmid-mediated quinolone resistance () genes among isolates.