Polymer-Based Drug Delivery Systems, Development and Pre-Clinical Status.

Background: The nanomedicine is considered as the application of nanotechnology in the medical field where nanoparticles are sized in the nanoscale range. Drug delivery technologies are becoming increasingly important as a scientific area of investigation. Controlled-release systems and drug-targeting systems represents an alternative to traditional delivery nanoparticles, and the use of polymers is increasing nowadays.

Heart Rate monitoring during physical exercise using wrist-type photoplethysmographic (PPG) signals.

Heart rate monitoring using wrist-type using photoplethysmographic (PPG) signals during subjects' intensive exercises is a challenging problem, since signals are strongly affected by motion artifacts caused by unexpected movements. This paper presents a method that uses both time and frequency characteristics of signals; using sparse signal reconstruction for high-resolution spectrum estimation. Experimental results on type data sets recorded from 12 subjects during fast running at peak speed of 15 km/hour.

Adherence to American society of health-system pharmacists surgical antibiotic prophylaxis guidelines in a teaching hospital.

Objective: Surgical site infections are the second most common type of adverse events occurring in hospitalized patients, whereas an estimated 40-60% of these infections are thought to be preventable. Choice of regimen, administration timing or duration of antibiotic prophylaxis is reported to be inappropriate in approximately 25-50% of cases. We tried to evaluate an antibiotic administration pattern for surgical antibiotic prophylaxis in a teaching hospital.

Chemoprotective effects of hesperidin against genotoxicity induced by cyclophosphamide in mice bone marrow cells.

The preventive effect of hesperidin as a flavonoid was investigated in mouse bone marrow cells against genotoxicity induced by cyclophosphamide. Mice were orally (gavages) pretreated with solutions of hesperidin at four different doses (50, 100, 200, and 400 mg/kg b.w.