Publications by authors named "Ahmad Sabry Mohamad"
Article Synopsis
- The study focuses on four individuals in Malaysia with a rare genetic combination of hemoglobin variants known as Hb G-Makassar and Hb E.
- All cases were discovered incidentally through routine screening methods, and while some had a history of unrelated anemia, others showed no symptoms at all.
- The findings underscore the importance of further research into the clinical implications and prevalence of rare hemoglobin variants in diverse populations.
Haemoglobin (Hb) G-Makassar is a rare Hb variant. It presents a diagnostic challenge as it imitates sickle Hb (Hb S) in standard electrophoresis and high-performance liquid chromatography assays requiring DNA analysis to confirm diagnosis. Both have point mutations in codon 6, exon 1 in the β-globin () gene with different pathogenicities.
View Article and Find Full Text PDFHuman hemoglobin of G-Makassar variant has been reported very rarely with Beta Thalassemia. In year 1969 Hb GMakassar was first identified in Makassar, Sulawesi (Celebes), Republic of Indonesia. The disease was first published in 1969 and 33 years later it has been reported at a family of Thailand origin.
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