Publications by authors named "Ahmad S Abu-Khadra"
Article Synopsis
- Quetiapine fumarate is a short-acting antipsychotic that typically requires multiple daily doses; this study aims to create a copolymer for controlled delivery of the drug.
- Hydroxypropyl methylcellulose K15M (HPMC K15M) is added to the formulation to enhance patient compliance and reduce side effects, with varying concentrations tested between 10-30%.
- The study utilized several analytical methods to examine the hydrogels' properties and found that increasing HPMC K15M concentration improved the drug's release profile, demonstrating a non-Fickian diffusion mechanism for drug release.
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