Publications by authors named "Ahmad Khoja"
Objective: Zenker diverticulum is a mucosal herniation at the pharyngoesophageal junction. Although open surgical myotomy is the conventional treatment, robust evidence on third-space flexible endoscopic myotomy is lacking. We assessed safety, effectiveness, and patient-reported outcomes of per-oral endoscopic myotomy (Z-POEM) in the largest reported single-center experience with this technique.
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- Malignant mesothelioma (MM), linked to asbestos exposure, is increasingly prevalent and resistant to treatment, making the study of its underlying mechanisms crucial.
- Researchers found that the platelet-derived growth factor receptor (PDGFR) ligand, PDGF-BB, boosts CTGF protein levels in MM cells without changing CTGF mRNA levels, indicating a unique regulation mechanism.
- PDGFR activation triggers the AKT pathway, which is vital for increasing CTGF protein expression, suggesting that targeting these pathways could be key in addressing MM malignancy.
Background: Surgical site infection (SSI) is one of the most common complications of abdominal surgery and is associated with substantial discomfort, morbidity and cost. The goal of this study was to describe the incidence, bacteriology and risk factors associated with SSI in patients undergoing abdominal surgery.
Methods: In this prospective cohort study, all patients aged 14 years or more undergoing abdominal surgery between Feb.