Publications by authors named "Ahmad I Kamaludin"

Article Synopsis
  • The study investigates the impact of preserving the pituitary stalk during surgery for craniopharyngiomas on various postoperative outcomes, including diabetes insipidus (DI) and anterior pituitary function (PF).
  • A meta-analysis of 33 studies involving 2366 patients found that preserving the pituitary stalk significantly reduced the risk of postoperative DI and abnormal anterior PF but showed no increase in incomplete resection or tumor recurrence rates.
  • The preservation strategy may be particularly challenging in pediatric patients, as they exhibited a higher risk of incomplete resection if the stalk was preserved.
View Article and Find Full Text PDF

Background: Despite years of research, the standard of care (SOC) treatment for grade 4 glioma has remained virtually unchanged for the last 2 decades. Autologous tumor lysate-loaded dendritic cell vaccination (DCVax-L), a novel immunotherapy, has demonstrated a significant survival benefit in a phase 3 trial.

Observations: A 34-year-old male presented with episodes of lightheadedness and was subsequently diagnosed with a large fronto-insulo-temporal tumor, likely to be high grade.

View Article and Find Full Text PDF

Background: Transfer of all severe TBI patients to a neurosurgical unit (NSU) has been advocated irrespective of levels of complexity and prognostic factors. Previous publications have suggested that only 50% of severe TBI patients in Ireland were managed in NSUs.

Aims: This study aims to audit severe TBI referrals to the National Neurosurgical Centre, to evaluate reasons for nonacceptance, assess for differences in the transferred and not transferred cohorts and to analyse observed and expected mortality rates.

View Article and Find Full Text PDF