Publications by authors named "Ahmad Hazri Ab Rashid"
This clinical trial aimed to evaluate the clinical efficacy of chitosan derivative hydrogel paste (CDHP) as a wound bed preparation for wounds with cavities. This study enrolled 287 patients, with 143 patients randomized into the CDHP group (treatment) and 144 patients randomized into the commercial hydroactive gel (CHG) group (control). The granulation tissue, necrotic tissue, patient comfort, clinical signs, symptoms, and patient convenience during the application and removal of the dressing were assessed.
View Article and Find Full Text PDFCharacterization of Acyl-CoA Oxidases from the Lipolytic Yeast SH14.
J Microbiol Biotechnol
July 2022
Article Synopsis
- The lipolytic yeast SH14 has three types of Acyl-CoA oxidases (ACOXs), each encoded by different genes, that play essential roles in the β-oxidation of fatty acids.
- Studies were conducted on mutant strains of SH14 to analyze growth and understand the specific functions of these isozymes using fatty acids as the only carbon source.
- The results showed that one isozyme specializes in short to medium-chain fatty acids (C6-C12), another in long-chain fatty acids (greater than C12), and the third has a broad preference, indicating that all three are necessary for complete β-oxidation of various fatty acid lengths.
Article Synopsis
- A new lipolytic yeast strain called SH14, found in oil palm compost, can use long-chain fatty acids as its only carbon source.
- Researchers developed a CRISPR-Cas9 genetic manipulation system specific to SH14 to enhance its capabilities for producing bio-based chemicals from renewable plant oils.
- By disrupting multiple acyl-CoA oxidase genes, the team created a β-oxidation mutant with a 70% success rate and demonstrated targeted integration of a lipase gene, showing the potential for improved industrial applications of SH14.
The present studies are to evaluate the ability of PB to induce weight loss and urine metabolite profile of Piper betle L. (PB) leaf extracts using metabolomics approach. Dried PB leaves were extracted with ethanol 70% and the studies were performed in different groups of rats fed with high fat (HFD) and normal diet (ND).
View Article and Find Full Text PDFPiper betle L. (PB) belongs to the Piperaceae family. The presence of a fairly large quantity of diastase in the betel leaf is deemed to play an important role in starch digestion and calls for the study of weight loss activities and metabolite profile from PB leaf extracts using metabolomics approach to be performed.
View Article and Find Full Text PDFA phenolic biosensor based on a zirconium oxide/polyethylene glycol/tyrosinase composite film for the detection of phenolic compounds has been explored. The formation of the composite film was expected via electrostatic interaction between hexacetyltrimethylammonium bromide (CTAB), polyethylene glycol (PEG), and zirconium oxide nanoparticles casted on screen printed carbon electrode (SPCE). Herein, the electrode was treated by casting hexacetyltrimethylammonium bromide on SPCE to promote a positively charged surface.
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