Use of computational fluid dynamics deposition modeling in respiratory drug delivery.

Introduction: Respiratory drug delivery is a surprisingly complex process with a number of physical and biological challenges. Computational fluid dynamics (CFD) is a scientific simulation technique that is capable of providing spatially and temporally resolved predictions of many aspects related to respiratory drug delivery from initial aerosol formation through respiratory cellular drug absorption.

Areas Covered: This review article focuses on CFD-based deposition modeling applied to pharmaceutical aerosols.