Heterotaxy syndrome, dextrocardia, ureteropelvic obstruction, endometriosis, and pulmonary hypertension in an adult with congenital heart defects: a case report.

Background: Heterotaxia is characterized by an abnormal positioning of the thoracic and/or abdominal organs, resulting in various physiological and hemodynamic implications. Congenital heart disease involves structural irregularities in the heart or major vessels within the chest, leading to functional challenges.

Case Presentation: We present a 26-year-old Arab female patient with a complex medical history involving heterotaxy, dextrocardia, congenital heart disease, and ureteropelvic junction obstruction diagnosed in her first year of life, followed by the identification of endometriosis in her early twenties.

Giant low-grade mucinous cystadenocarcinoma of the ovary: A case report and literature review.

Introduction: Mucinous ovarian cancer (MOC) is a rare subtype of epithelial ovarian carcinoma, comprising 3-5 % of all ovarian cancer cases. It typically affects women aged 20 to 50 years and is often diagnosed at an early stage, with most patients presenting with early-stage disease. However, giant mucinous cystadenocarcinomas are extremely rare and pose significant diagnostic and therapeutic challenges.

Mimicking rib osteochondroma as pulmonary nodule in a pediatric patient: A case report from Damascus, Syria.

Osteochondromas, the most frequent type of bone tumor, develop from the metaphysis region of bones. Osteochondroma often occurs in bones, however, it is rare when it comes to rib tumors. It is often asymptomatic and observed incidentally.

Contraceptives Knowledge and Perception: A Cross-Sectional Study Among Future Pharmacists in Jordan.

Background: Unintended pregnancy has huge burdens on healthcare resources and society. Contraception is essential to reduce it, and pharmacists are usually the first healthcare providers who are asked for advice about contraceptives. Therefore, the study aimed to evaluate future pharmacists' knowledge, awareness, and perceptions of contraceptive methods and assess the factors influencing their knowledge, awareness, and perceptions.

Evaluating the Sensitivity, Specificity, and Accuracy of ChatGPT-3.5, ChatGPT-4, Bing AI, and Bard Against Conventional Drug-Drug Interactions Clinical Tools.

Background: AI platforms are equipped with advanced ‎algorithms that have the potential to offer a wide range of ‎applications in healthcare services. However, information about the accuracy of AI chatbots against ‎conventional drug-drug interaction tools is limited‎. This study aimed to assess the sensitivity, specificity, and accuracy of ChatGPT-3.

Neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio in stroke-associated pneumonia: a systematic review and meta-analysis.

Background: Predicting stroke-associated pneumonia (SAP) is crucial for intensifying preventive measures and decreasing morbidity and mortality. This meta-analysis aims to evaluate the association between baseline neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), and platelet-lymphocyte ratio (PLR) with SAP and to determine the strength of the association.

Methods: The Web of Science, SCOPUS, and PUBMED databases were searched to find eligible studies.

The evidence from clinical trials on Gout medicines effect on COVID-19: A protocol for systematic review and meta-analysis.

Aim: To evaluate the available evidence from clinical trials on the efficacy of gout medicines against COVID-19.

Design: Systematic review and Meta-analysis.

Methods: We are systematically searching five databases [PubMed, Embase, CT.

The Management of Myocardial Injury Related to SARS-CoV-2 Pneumonia.

The global evolution of the SARS-CoV-2 virus is known to all. The diagnosis of SARS-CoV-2 pneumonia is expected to worsen, and mortality will be higher when combined with myocardial injury (MI). The combination of novel coronavirus infections in patients with MI can cause confusion in diagnosis and assessment, with each condition exacerbating the other, and increasing the complexity and difficulty of treatment.

The evidence from clinical trials on colchicine and corticosteroids' effect on COVID-19: a systematic review and meta-analysis.

Objectives: With no clear end for the outbreak, identifying the drugs that are effective in COVID-19's management is of utmost importance to reduce the impact on the general population and the healthcare systems.

Methods: This is a systematic review and a meta-analysis evaluating the evidence from clinical trials on the effect of colchicine and corticosteroids against COVID-19. In this review, we have systematically searched five databases [(PubMed, Embase, clinicaltrials.

The Association between Chronic Heroin Smoking and Chronic Obstructive Pulmonary Disease.

Introduction: Little is known about the correlation between chronic obstructive pulmonary disease (COPD) and heroin smoking. Heroin smoking is a recent underinvestigated problem. The goal of this study is to study the impact of heroin smoking among COPD patients.

Prevalence, risk assessment, and predictors of osteoporosis among chronic obstructive pulmonary disease patients.

The link between chronic obstructive pulmonary disease (COPD) and osteoporosis is unclear and yet to be understood. The study goals were to detect the prevalence of osteoporosis and investigate its predictors among COPD patients. This is a longitudinal study conducted in a tertiary care setting.

Misinformation, perceptions towards COVID-19 and willingness to be vaccinated: A population-based survey in Yemen.

Background: Since the beginning of the COVID-19 outbreak, many pharmaceutical companies have been racing to develop a safe and effective COVID-19 vaccine. Simultaneously, rumors and misinformation about COVID-19 are still widely spreading. Therefore, this study aimed to investigate the prevalence of COVID-19 misinformation among the Yemeni population and its association with vaccine acceptance and perceptions.

Healthcare workers' knowledge, preparedness, counselling practices, and perceived barriers to confront COVID-19: A cross-sectional study from a war-torn country, Yemen.

Background: The coronavirus disease of 2019 (COVID-19) represents a difficult challenge and could have devastating consequences for the healthcare system and healthcare workers in war-torn countries with poor healthcare facilities such as Yemen. Our study aimed to evaluate the knowledge, preparedness, counselling practices of healthcare workers regarding COVID-19, and the perceived barriers to adequately prevent and control COVID-19 in Yemen.

Methods: Healthcare workers (HCWs) from major healthcare facilities participated in this cross-sectional study.

Denitrification in wetlands: A review towards a quantification at global scale.

Research to understand the nitrogen cycle has been thriving. The production of reactive nitrogen by humans exceeds the removal capacity through denitrification of any natural ecosystem. The surplus of reactive nitrogen is also a significant pollutant that can shift biological diversity and distribution, promotes eutrophication in aquatic ecosystems, and affects human health.

cytotoxic and antimicrobial activities of (Roxb) bark.

Background: The study was focused on evaluating cytotoxic and antimicrobial activities of (Roxb.) bark through pharmacological screening.

Materials And Methods: The bark was extracted using different solvents, for example, dichloromethane, ethyl acetate, methanol, and aqueous for obtaining the organic fractions.

Comparison of cystatin C and creatinine-based estimated glomerular filtration rate equations among elderly chronic kidney disease patients attending a tertiary care hospital: A prospective cross-sectional study .

Background: Serum creatinine has been solely used in clinical practice to identify chronic kidney disease (CKD) staging in the elderly population. Serum cystatin C is believed to more accurately define the CKD staging and is also ratified as an endogenous biomarker by Kidney Disease Improving Global Outcomes (KDIGO) guidelines.

Material And Methods: A total of 300 elderly Malay participants (age ≥ 65 years) with CKD, attending the Hospital University Sains Malaysia were included in the study.

Osteoporosis among Patients with Chronic Obstructive Pulmonary Disease: Systematic Review and Meta-analysis of Prevalence, Severity, and Therapeutic Outcomes.

Chronic obstructive pulmonary disease (COPD) can be associated with systemic inflammatory trademarks and can coexist with other chronic debilitating diseases such as osteoporosis, which is considered among the most serious comorbidities of COPD. In this review, we aimed at finding answers for the following questions and tried to encapsulate the available literature: (1) how prevalent is osteoporosis among patients with COPD? (2) What are severity patterns of osteoporosis in case of COPD? (3) What are the therapeutic outcomes for patients with osteoporotic COPD? The total number of patients with COPD from all studies was 3815, majority of which were male (2658) representing 69.67% of patients.

Elaboration of ammonio methacrylate copolymer based spongy cationic particles via double emulsion solvent evaporation process.

The aim of present work is to investigate systematic study of the preparation of biodegradable particles via double emulsion solvent evaporation technique. The used formation is based on cationic ammonium methacrylate copolymer Eudragit® RS 100, without the use of any stabilizer. The effect of process parameters like ultra turrax® stirring speed and stirring time, ultrasonication time, polymer amount, and volume of outer aqueous phases on the colloidal properties of particles was investigated.

In situ evaluation of the fruit and oil characteristics of the main Lebanese olive germplasm.

Background: Very little information is available on the characteristics of the Lebanese olive germplasm. Therefore, the aim of this work was to evaluate the fruit and oil characteristics of the main Lebanese olive varieties (Aayrouni, Abou chawkeh, Baladi, Del and Soury) from two successive crop seasons (2010-2011).

Results: All of the genotypes had medium-high oil content in the fruit, indicating their suitability for oil production; Aayrouni had particularly high values.

Fluorescent-magnetic Janus particles prepared via seed emulsion polymerization.

Anisotropic polymeric colloidal or Janus particles possessing simultaneous magnetic and fluorescent properties were successfully prepared via the swelling-diffusion or the in situ emulsion polymerization method. In the swelling-diffusion process, magnetic emulsions (an organic ferrofluid dispersed in aqueous medium) were synthesized and used for seeds of submicron magnetic Janus particles. After swelling the anisotropic particles obtained by 1-pyrene-carboxaldehyde fluorescent dye dissolved in tetrahydrofuran, well-defined fluorescent-magnetic Janus particles were produced.

Polymer encapsulation of inorganic nanoparticles for biomedical applications.

Hybrid inorganic colloidal particles have attracted a great attention in the last years, and they have been largely used in various applications and more particularly in biomedical nanotechnology. Recently, they are used as carriers for biomolecules, and exploited for use in microsystems, microfluidics and in lab-on-a chip based bionanotechnology. Various kinds of hybrid particles can be listed starting from classical inorganic nanoparticles such as silica, gold, silver, iron oxide and those exhibiting intrinsic properties such as semiconducting nanoparticles (e.

Synthesis and characterization of thermally and glucose-sensitive poly N-vinylcaprolactam-Based microgels.

Temperature and glucose sensitive microgels were prepared via radical precipitation polymerization, using N-vinylcaprolactam (NVCL) as the main monomer, N,N-methylenebisacrylamide (MBA) as a crosslinker, V50 as initiator and 4-vinylphenylboronic acid (VPBA) as a functional monomer. The LCST of homopoly (NVCL) was first determined and found to be around 33 degrees C. The preparation of microgels was examined as a function of crosslinker (MBA) and VPBA amount in the polymerization recipe.

Silica-based nanoparticles for biomedical applications.

In this short review we highlight novel uses of silica-based nanoparticles (NPs) in the biomedical sector. Silica NPs are widely used in nanotechnology because they are easy to prepare and inexpensive to produce. Their specific surface characteristics, porosity and capacity for functionalization make them good tools for biomolecule detection and separation, providing solid media for drug delivery systems and acting as contrast agent protectors.

Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients.

Object: Although a growing number of authors currently advocate surgery to treat low-grade gliomas, controversy still persists, especially because of the risk of inducing neurological sequelae when the tumor is located within eloquent brain areas. Many researchers performing preoperative neurofunctional imaging and intraoperative electrophysiological methods have recently reported on the usefulness of cortical functional mapping. Despite the frequent involvement of subcortical structures by these gliomas, very few investigators have specifically raised the subject of fiber tracking.

Intraoperative mapping of the subcortical language pathways using direct stimulations. An anatomo-functional study.

Functional neuroimaging has improved pre-planning of surgery in eloquent cortical areas, but remains unable to map white matter. Thus, tumour resection in functional subcortical regions still presents a high risk of sequelae. The authors successfully used intraoperative electrical stimulations to perform subcortical language pathway mapping in order to avoid postoperative definitive deficit, and correlated these functional findings with the anatomical location of the eloquent bundles detected using postoperative MRI.