Higher vedolizumab serum levels do not increase the risk of adverse events in patients with inflammatory bowel disease.

Although its mechanism of action may confer a safety benefit, vedolizumab has still been associated with adverse events (AE). We investigated whether inflammatory bowel disease (IBD) patients with higher trough vedolizumab serum levels experienced an increased risk of AEs. This was a retrospective study of 76 IBD patients with at least one measurement of serum vedolizumab available.