T-cell lymphoma is an extremely rare form of malignancy in the female genital tract. Most of the reported cases of lymphoma are B-cell lymphomas. A few cases of primary T-cell lymphomas involving the vagina or the vulva have been reported.
View Article and Find Full Text PDFContext: Thoracic SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is a recently described aggressive neoplasm of young smokers defined by inactivating mutations and characterized by cells with rhabdoid morphology, high mitotic activity, and abundant necrosis.
Objective: Describe and compare 3 unusual presentations of SMARCA4-UT in older adults, including one presenting as a metastatic lesion mimicking a primary bone sarcoma. Discuss the molecular characteristics of SMARCA4-UT and their relationship to nonsmall-cell lung carcinomas with .
Background: Despite significant progress in clinical management, colorectal cancer (CRC) remains the third most common cause of cancer-related deaths. A positive association between PYCR2 (pyrroline-5-carboxylate reductase-2), a terminal enzyme of proline metabolism, and CRC aggressiveness was recently reported. However, how PYCR2 promotes colon carcinogenesis remains ill understood.
View Article and Find Full Text PDFBackground: Delirium is a common, often undiagnosed disorder in elderly patients, but no studies have been conducted in Saudi Arabia.
Objectives: To determine the prevalence of delirium among elderly patients on admission and to identify associated factors.
Design: A cross-sectional study.