Publications by authors named "Ahmad Aldwaikat"

Article Synopsis
  • Sleep-disordered breathing (SDB) is prevalent in Veterans, with a study analyzing the rates of central sleep apnea (CSA), obstructive sleep apnea (OSA), and a combination of both (COSA).
  • From 90 screened patients, 71% had COSA, 20% had CSA only, and 9% had OSA only, with only 24.4% of those with CSA or COSA responding well to PAP therapy.
  • Although the initial response to PAP therapy was low, both responsive and nonresponsive groups showed significant improvements in apnea rates after 60 days of treatment.
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Purpose: Arousals may contribute to the pathogenesis of sleep-disordered breathing (SDB) and central sleep apnea (CSA). We aimed to determine the effect of the nonbenzodiazepine hypnotic zolpidem on the frequency of respiratory-related arousals and central apnea in patients with moderate-to-severe SDB. We hypothesized that zolpidem decreases the severity of SDB by decreasing the frequency of respiratory-related arousals.

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Mouse models of age-related macular degeneration (AMD) such as Ccl2 and Ccl2/Cx3cr1 have not yet been fully characterized ultrastructurally. Although we have previously shown extranuclear DNA (enDNA) leakage into the cytoplasm and damaged mitochondria in the retinal pigment epithelium (RPE) of these AMD mouse models, little is known about the state of their vascular capillaries of the retina and choroid. Our ultrastructural survey shows that the aberrations were not restricted to the RPE cells, but also extended to the vasculature of the retina and choroid.

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