Work-related injuries and compliance with personal protective equipment among migrant workers in Al-Qassim, Saudi Arabia.

Migrant workers constitute nearly one-third of Saudi Arabia's population, with a significant portion engaged in low-skilled manual labour. Limited data exists on work-related injuries and the use of personal protective equipment (PPE) among workers. The current cross-sectional survey focused on seven occupational groups, (i.

Novel mutation in alpha-spectrin gene in Saudi patients with hereditary spherocytosis.

Hereditary spherocytosis (HS) is the most common hereditary hemolytic disorder induced by red blood cell (RBC) membrane defect. This study was undertaken to determine mutations in genes associated with RBC membrane defect in patients with HS such as α-spectrin gene (SPTA1), β-spectrin gene (SPTB), ankyrin gene (ANK1), band 3 anion transport gene (SLC4A1) and erythrocyte membrane protein band 4.1 gene (EPB41).

Isolated benign neutropenia in healthy individuals from Saudi Arabia's central region: A comprehensive study.

Objectives: Neutrophils are the most common cell types in circulation and are considered the first line of defense in the immune system against microorganisms. This study was undertaken to investigate the occurrence of isolated benign neutropenia (IBN) among healthy individuals in the central region of Saudi Arabia.

Methods: This retrospective study analyzed complete blood count tests as part of routine checkups for chronic health conditions from April to September 2022.

Assessment of osteoporosis in patients with type 2 diabetes mellitus: A study from the central region of Saudi Arabia.

Objectives: To understand the impact of diabetes on bone mineral density and whether it increases the likelihood of osteoporosis.

Methods: This study was performed on 327 Saudis (aged >40 years) who were screened for osteoporosis and diabetes mellitus (DM). The levels of osteoporosis were determined by an estimation of Bone mineral density (BMD) using a DEXA scan examination.

Modulation of mice immune responses against Schistosoma mansoni infection with anti-schistosomiasis drugs: Role of interleukin-4 and interferon-gamma.

Objective: () is endemic in Africa, the Middle East, South America, and the Caribbean. This study investigated the modulation of immune response against through estimation of interleukin-4 (IL-4) (Th2 cytokine) and interferon-gamma (INF-γ) (Th1 cytokine) under the effect of anti-schistosomal drugs.

Methods: Laboratory bred female albino mice ( = 120) were divided into the following groups: untreated mice, infected mice, infected mice treated with artemisinin (ART), arachidonic acid (ARA), nifedipine or praziquantel (PZQ).

Evaluation of hematological parameters in dyspepsia patients infected with : A retrospective study from the Central Region of Saudi Arabia.

Objectives: To evaluate the hematological parameters in dyspepsia patients infected with () infection from Al Qassim province of Kingdom of Saudi Arabia (KSA).

Methods: This retrospective study was carried out in Dr. Sulaiman Al-Habib Hospital, Al Qassim, KSA.

Full Dose Cyclophosphamide with the Addition of Fludarabine for Matched Sibling Transplants in Severe Aplastic Anemia.

The recommended therapy for severe aplastic anemia (SAA) in younger patients with a matched sibling donor (MSD) is allogeneic hematopoietic cell transplantation (allo-HCT). A number of conditioning regimens and protocols have been used for these patients. Here we report a homogeneous cohort of SAA patients receiving a uniform transplantation protocol.

Outcomes of allogeneic hematopoietic cell transplant for acute myeloid leukemia in adolescent patients.

Patients between 14 and 22 years old are underrepresented in both adult and pediatric studies. We analyzed the outcomes of 94 consecutive patients aged between 14 and 22 who underwent myeloablative matched related-donor transplant while in first or second complete remission. We studied the impact of disease type, remission status, ELN risk group, ABO mismatch, time from diagnosis to transplant, patient and donor age, conditioning type, stem cell source, and the year of transplant on transplant outcomes.

Early and late effects of therapeutic plasma exchange in patients with systemic lupus erythematosus and antineutrophil cytoplasmic antibody-associated vasculitis: A single-center experience.

Therapeutic plasma exchanges (TPE) is considered as one of the treatment modalities that is used in systemic autoimmune diseases. This study aimed to describe the early and late effect of TPE in patients with systemic lupus erythematosus (SLE) and antineutrophil cytoplasmic antibody-associated vasculitis (AAV) presented with acute kidney injury (AKI). Retrospective study comprised patients with SLE and AAV with AKI seen between January 2000 and June 2014 at King Faisal Specialist Hospital and Research Center in Riyadh.

Philadelphia chromosome-positive lymphoblastic lymphoma-Is it rare or underdiagnosed?

Lymphoblastic lymphomas (LBLs) are neoplasms of precursor B and T cells; they are considered in the same spectrum as precursor B and T cell acute lymphoblastic leukemia (ALL). The World Health Organization classification classifies both LBL and ALL as one disease entity. While chromosome abnormalities are well defined with all of their therapeutic and prognostic implications in ALL, these are not well studied in LBL.

Nephrotic syndrome is a rare manifestation of IGA nephropathy.

Nephrotic syndrome is a rare presentation of IgA nephropathy. The degree of proteinuria in IgA nephropathy predicts poor prognosis. We herein report a teenager with IGA nephropathy, the nephrotic syndrome and segmental glomerular scars who after developing complications from high dose corticosteroid therapy was successfully treated with tacrolimus and low dose prednisone.