Accelerating antimicrobial peptide design: Leveraging deep learning for rapid discovery.

Antimicrobial peptides (AMPs) are excellent at fighting many different infections. This demonstrates how important it is to make new AMPs that are even better at eliminating infections. The fundamental transformation in a variety of scientific disciplines, which led to the emergence of machine learning techniques, has presented significant opportunities for the development of antimicrobial peptides.

Mild and classical solutions to fractional Cauchy problem on time scales.

In this manuscript, aims to examine the uniqueness and existence of impulsive non-local conditions, as well as classical and mild solutions to the fractional Cauchy problem in time scales. The main results are derived by the Gronwall inequality and the Banach fixed point theorem in time scales. Eventually, we offered an example to demonstrate the suitability of the conclusions on the fractional Cauchy issue on a time scale.

Development of a novel light-sensitive PPG model using PPG scalograms and PPG-NET learning for non-invasive hypertension monitoring.

Background And Objective: Photoplethysmography (PPG) signals provide a non-invasive method for monitoring cardiovascular health, including blood pressure levels, which are critical for the early detection and management of hypertension. This study leverages wavelet transformation and special purpose deep learning model, enhanced by signal processing and normalization, to classify blood pressure stages from PPG signals. The primary objective is to advance non-invasive hypertension monitoring, improving the accuracy and efficiency of these assessments.

From Insights to Impact: Understanding Cancer Screening Choices through Mixed-Methods.

Objective: The main objective of this comprehensive mixed-methods investigation conducted in Jordan were to explore and understand men's engagement in cancer screening.

Methods: The research employed a mixed-methods approach, combining a survey with 209 participants and focus group interviews with 30 individuals. The survey involved quantitative data collection methods to gather information on cancer screening participation rates among men in Amman.

Analyzing Depressive Symptoms Among Elderly Cancer Patients: A Comprehensive Examination of Demographic and Medical Correlates.

Objective: This study aimed to explore the relationship between depressive symptoms and demographic as well as health-related variables in elderly individuals diagnosed with cancer.

Methods: A cohort of 50 elderly cancer patients participated in the study. Data collection involved the completion of surveys and assessments encompassing demographic characteristics, medical profiles, levels of depression, cognitive functioning, activities of daily living, and perceived social support.

Overlapping otolaryngologic surgery: Safety and efficacy.

Background: Surgical procedures scheduled staggered between two operating rooms increase efficiency by eliminating turnover time. However, the practice might increase the surgeon's fatigue. Overlapping surgery has been assumed to be safe because no critical portions of procedures are performed simultaneously in two rooms, but there is little evidence in the literature to support that assumption for otolaryngologic surgery, and there is no evidence comparing non-overlapping and overlapping surgical outcomes for a single surgeon with all confounding factors controlled.

Factors Influencing Prostate Cancer Screening Intentions in Lebanese Men.

Objective: The objective of this study is to investigate the perceived obstacles and willingness of Lebanese men aged 40 and above to undergo screening for prostate cancer.

Material And Method: A cross-sectional research design was employed. The study utilized a survey questionnaire to collect data on various factors influencing screening behaviors.

The Effectiveness of P6 and Auricular Acupressure as a Complimentary Therapy in Chemotherapy-Induced Nausea and Vomiting Among Patients With Cancer: Systematic Review.

Background: Chemotherapy-induced nausea and vomiting (CINV) is one of the most prevalent and distressing side effects of chemotherapy among patients with cancer worldwide. Despite continuing advances in antiemetic medicines, nausea and vomiting associated with cancer chemotherapy remain a substantial therapeutic concern for many patients. However, P6 and Auricular acupressure (AA) have been recognized as potential therapy for managing chemotherapy-induced nausea and vomiting.

Characterization of Laryngopharyngeal Reflux in the Elderly Population.

Introduction: Laryngopharyngeal reflux (LPR) often is not diagnosed due to its presentation without heartburn. The aim of this study was to analyze the signs and symptoms of elderly patients undergoing treatment for LPR using subjective as well as objective measures including strobovideolaryngoscopies, 24-hour pH studies, and manometry to highlight appropriate considerations for diagnosis and treatment.

Methods: This was a retrospective review of patients with laryngopharyngeal reflux who were seen from January 2010 to February 2021 in the practice of the senior author (Robert T.

An Exploration of the Risk Factors, Severity, and Sequelae of Vocal Fold Hemorrhage in a Population of Voice Patients Before and After Diagnosis.

Background: Vocal fold hemorrhage (VFH) is the rupture (usually acute) of a blood vessel within the true vocal fold. The long-term sequelae of VFH on the mucosal wave (MW) and glottic gap on video stroboscopy remain understudied. The primary objective of this study was to investigate the short-term and long-term consequences of VFH through measured and rated analysis of the mucosal wave and glottic gap.

Misdiagnosis of Vocal Fold Nodules.

Introduction: Benign vocal fold masses (BVMs) include nodules, polyps, cysts, and other pathology. Nevertheless, some otolaryngologists and other physicians utilize "vocal fold nodules" as an umbrella diagnosis for vocal fold masses. Patients subsequently evaluated by a laryngologist are found to have a different vocal fold mass, which often has a different prognosis and treatment plan compared to nodules.

Impulsive fractional order integrodifferential equation via fractional operators.

In this paper, we establish the existence and uniqueness of the solution to fractional equations abstract integrodifferential equation with impulsive as [Formula: see text] where [Formula: see text] and we used the fixed point theorems due to Banach space. The main conclusion is obtained by using fractional calculus, operator semigroup and fixed point theorem. Finally, in support, an example is presented to validate the obtained results.

An Overview of the Effect of Age at Time of Cochlear Implantation on Language Outcomes in Jordan: A Retrospective Cohort Study.

Introduction: Cochlear Implantation (CI) surgery has long been used as an effective treatment for children with bilateral profound sensorineural hearing loss who failed to benefit from the use of hearing aids. Among other factors, the age at which implantation is done is thought to have an effect on the speech progression outcome of patients postoperatively.

Objectives: The Jordanian CI Program has limited resources, and Jordan has an underdeveloped early screening and intervention program for deafness.

Nodular Fasciitis and Myxolipoma of the Larynx: A rare case report with brief literature review.

Nodular fasciitis (NF) is a peculiar, rapid-growing soft tissue lesion, typically appearing in subcutaneous tissue. Approximately 20% of NF occurs in the head and neck region, where they can involve any anatomic site. Laryngeal involvement, however, is quite rare.

Perspectives on COVID-19 Vaccines and Its Hesitancy Among Jordanian Population.

Background Since the spread of the COVID-19 virus, governments are putting significant resources into ending the pandemic. Vaccination arises as the best solution to get back to our everyday lives. However, we are now facing vaccine hesitancy, which is a critical problem.

COVID-19 and laryngological surgery.

In 2019, the emergence of the novel SARS-CoV-2 virus in Wuhan, China transformed society and caused major changes in medical care. Efforts to implement protocols to keep providers and their staffs safe during care of all patients ensued. Within the field of laryngology, the risk of aerosol generation and viral spread was among the highest in medicine.

The macroscopic limit to synchronization of cellular clocks in single cells of Neurospora crassa.

We determined the macroscopic limit for phase synchronization of cellular clocks in an artificial tissue created by a "big chamber" microfluidic device to be about 150,000 cells or less. The dimensions of the microfluidic chamber allowed us to calculate an upper limit on the radius of a hypothesized quorum sensing signal molecule of 13.05 nm using a diffusion approximation for signal travel within the device.

Tracheobronchopathia osteochondroplastica in the setting of COVID-19.

Tracheobronchopathia osteoplastica (TO) is a rare, benign disease of unknown etiology, primarily affecting the major tracheobronchial tree, characterized by irregular nodular calcifications of the cartilaginous component of the inner wall of the tracheobronchial tree while sparing the posterior wall, leading to progressive narrowing of the airway. We report the case of a 60-year-old male otherwise healthy nonsmoker, who complained of chronic breathing discomfort and recurrent chest infections and was found to have TO according to radiographic, microlaryngoscopic, and biopsy findings. He experienced a flare up with worsening of disease progression after years of being in stable condition, after his infection with SARS-CoV-2.

Neonatal Screening for Congenital Hearing Loss in the North of Jordan; Findings and Implications.

Background: Congenital hearing loss is one of the important illnesses that affect newborns. Early diagnosis and treatment are a challenge for medical authorities in developing countries to improve children's functional, intellectual, emotional, and social abilities. We aimed to study the prevalence of congenital hearing loss in northern Jordan community and identify factors that could affect hearing screening protocol.

Cardiac cachexia among patients with chronic heart failure: A systematic review.

Introduction: Despitecardiac cachexia being a prevalent health problem among heart failure (HF) patients, it has been given little attention by nursing researchers. Therefore, this study aims to conduct a systematic review that investigates cardiac cachexia among patients with HF.

Methodology: A systematic review will be performed according to the PRISMA guidelines to assess the findings of twelve selected studies which meet the inclusion criteria of the systematic review research.

Efficacy of pillar implants to reduce snoring and daytime sleepiness.

Objective: To measure the efficacy of pillar implants in reducing snoring.

Materials And Methods: A total of 30 adult patients who underwent pillar implants were assessed preoperatively and at 1, 3, 6 and 12 months after the implantation. Improvement was measured using snoring frequency, visual analog scale for snoring loudness, and Epworth sleepiness scale for daytime sleepiness.

The feasibility of vagal nerve stimulation revision surgery and surgical techniques: a retrospective review.

Background: With the large number of VNS implants performed worldwide, the need for removal or replacement of the device in selected cases is emerging, this removal or replacement of VNS can be challenging.

Aims/objective: To describe the feasibility and safety of revising vagal nerve stimulation surgery in terms of the indications, surgical techniques, and outcomes.

Materials And Methods: A retrospective study, a series of eight cases with VNS implants that needed revision surgery have been reviewed, four devices were completely removed and four were only revised.

The impact of COVID-19 outbreak on otolaryngology practice, jordanian experience: A qualitative study.

Background: In response to the rapid spread of coronavirus disease 2019 (COVID-19) caused by "severe acute respiratory syndrome coronavirus 2" (SARS-CoV-2), many countries including Jordan have implemented strict lockdowns. These lockdowns were associated with temporary suspension of all outpatient clinics and all elective (Non emergent, non-oncologic) surgical procedures.

Objective: We aimed to report the impact of COVID-19 outbreak on otolaryngology practice in Jordan.