Durability of COVID-19 humoral immunity post infection and different SARS-COV-2 vaccines.

Background: The global challenge posed by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been a major concern for the healthcare sector in recent years. Healthcare workers have a relatively high risk of encountering COVID-19 patients, making protective immunity against SARS-CoV-2 is a priority for them. This study aims to evaluate the longitudinal measurement of SARS-CoV-2 IgG spike protein antibodies in healthcare workers (HCWs) after COVID-19 infection and after receiving the first and second doses of SARS-CoV-2 vaccines, including Pfizer-BioNTech (BNT162b2) and Oxford-AstraZeneca (AZD1222).

Comparative Metabolic Characterization of Extraintestinal Pathogenic Blood Isolates from Saudi Arabia.

Background: The prevalence of bloodstream infections caused by extraintestinal pathogenic (ExPEC) has increased substantially. E. ST131 is one of the dominant ExPEC clones among E.

Seroprevalence of SARS-CoV-2 among high-risk healthcare workers in a MERS-CoV endemic area.

Introduction: Healthcare workers (HCWs) in Saudi Arabia are a unique population who have had exposures to the Middle East Respiratory Syndrome coronavirus (MERS-CoV) and Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It follows that HCWs from this country could have pre-existingMERS-CoV antibodies that may either protect from coronavirus disease 2019 (COVID-19) infection or cause false SARS-CoV-2 seropositive results. In this article, we report the seroprevalence of MERS-CoV and SARS-CoV-2 among high-risk healthcare workers in Riyadh city, Saudi Arabia.

IL-35 and IL-37 are negatively correlated with high IgE production among children with asthma in Saudi Arabia.

Background: Asthma is one of the most prevalent inflammatory disorders among children in Saudi Arabia.

Objective: This study aimed to determine the correlation between the serum levels of vitamin D, immunoglobulin E (IgE), and cytokine (interferon-gamma (IFN-γ), interleukin (IL)-1β, IL-4, IL-6, IL-10, IL-13, IL-35, and IL-37) in relation to the severity of disease in patients with asthma.

Methods: This case-control study was carried out at King Abdullah Specialist Children's Hospital, Saudi Arabia, and included 48 patients with asthma and 47 matched controls, aged 6-14 years.

Comparative phenotypic characterization identifies few differences in the metabolic capacity between ST131 subclones.

Background: Extraintestinal pathogenic (ExPEC) is responsible for causing many infections such as urinary tract infections (UTIs). The current dissemination of the multidrug resistant (MDR) ExPEC clone, sequence type 131 ( ST131), poses a real threat to public health worldwide. This study aimed to determine and compare the metabolic capacity of a collection of ExPEC isolates including ST131, non-ST131 and various ST131 subclones, and sought to assess the association between antimicrobial resistance and metabolic capacity of ST131 isolates.

Microbial Diversity of Some Sabkha and Desert Sites in Saudi Arabia.

Several studies isolated fungal and bacterial species from extreme environments, such as Sabkha and hot deserts, as their natural habitat, some of which are of medicinal importance. Current research aimed investigating the microbial (fungi and bacteria) diversity and abundance in Sabkha and desert areas in Saudi Arabia. Soil samples from nine different geographical areas (Al-Aushazia lake, AlQasab, AlKasar, Tabuk, Al-Kharj, Al-Madina, Jubail, Taif and Abqaiq) were collected and cultured for microbial isolation.

Prevalence and molecular characteristics of sequence type 131 clone among clinical uropathogenic isolates in Riyadh, Saudi Arabia.

Background: The antimicrobial resistance of extraintestinal pathogenic (ExPEC) has progressively been reported worldwide. This resistance has been ascribed to global dissemination of a single clone, namely sequence type 131 ( ST131). The main goal of this study is to determine the prevalence and molecular traits of ST131 and its subclones among clinical urine isolates in Riyadh, Saudi Arabia.

Morphological and molecular insights of a new species of trypanorhynchid cestode parasite, Nybelinia exostigmi, in the Narrowstripe cardinal fish Apogon exostigma.

Forty specimens of the Narrowstripe cardinal fish Apogon exostigma were examined for gastrointestinal helminthes, and 62.5% were infected with a new trypanorhynchid larval cestode parasite. The morphology of its larval stage was studied based on light and scanning electron microscopy.

Prevalence of Multidrug Resistance and Extended-Spectrum -Lactamase Carriage of Clinical Uropathogenic Isolates in Riyadh, Saudi Arabia.

The prevalence of extended-spectrum -lactamase-producing (ESBL-producing ) has recently increased worldwide. This study aims at determining the antimicrobial susceptibility patterns of a collection of clinical urine isolates and evaluating the ESBL carriage of these isolates at phenotypic and genotypic levels. A total of 100 urine isolates were collected at a tertiary healthcare centre in Riyadh from January 2018 to March 2018.

Association analysis between four vitamin D receptor gene polymorphisms and developmental dysplasia of the hip.

Developmental dysplasia of the hip (DDH) is a congenital condition characterized by abnormality in acetabulum size and/or shape. The incidence rate of DDH differs between different populations with risk factors including positive family history, breech presentation, sex, firstborn status, side of the hip, mode of delivery and oligohydramnios. It is recognized that DDH has a genetic component that exhibit autosomal dominant patterns.