Background: Colorectal carcinoma is one of the main causes of cancer death in the worldwide with a decrease survival rate in relationship with a later diagnosis of advanced disease.
Aims: This study highlights the particular epidemiological, clinicopathological and immunohistochemical colorectal cancer profile. Indeed, our results differ markedly from that reported in the literature.
Background: The p73 gene encodes a nuclear protein that is highy homologous to p53. p73 also shares some common functions with p53 protein indicating that p73 gene is a p53-like tumor suppressor.
Aim: In this study, we examined by immunohistochemestry the p73 expression on 120 cases of colorectal carcinomas and evaluated its implication in carcinogenesis.
Eur J Gastroenterol Hepatol
August 2007
Background: Celiac disease is reported to be common among North Africans, particularly Tunisians. Nevertheless, the prevalence of coeliac disease in the general population has not been previously investigated.
Objective: This study aimed to determine the prevalence of celiac disease among children in Tunisia and to describe the clinical profile of the screened patients.