Role of serum ferritin in assessment of disease activity in acute & chronic leukemia.

Serum ferritin (SF) was estimated using double antibody sandwich ELISA in 83 patients of acute and chronic leukemia at various stages of the disease. In 35 patients of acute lymphoblastic leukemia (ALL) in remission, the SF levels fell significantly from 550.63 ng/ml at presentation to 319.

Alcohol and coronary artery disease.

Alcohol affects the heart and circulation in several ways. Chronic alcohol consumption can be associated with a variety of cardiovascular disorders, ranging from hypertension and stroke to heart failure and sudden death. At the same time an inverse correlation has been found between moderate drinking and incidence of coronary artery disease, perhaps due to its favourable effects on lipoprotein levels.

Serum & tissue magnesium content in patients of aluminium phosphide poisoning and critical evaluation of high dose magnesium sulphate therapy in reducing mortality.

Role of high dose magnesium sulphate therapy was evaluated in 50 patients of Aluminium Phosphide (AIP) poisoning. Simultaneously serum and RBC magnesium levels were studied in these patients at six different points within first 24 hours. In non-survivors magnesium content of various tissues (brain, stomach, kidneys, liver, lungs and heart) was also estimated.

Indirect assessment of acute effects of ethyl alcohol on coronary circulation in patients with chronic stable angina.

Acute effects of ethyl alcohol on left ventricular performance, haemodynamic and electrocardiographic response to treadmill exercise test were studied in 20 patients with chronic stable angina. Following ingestion of 80 ml of whisky (43% ethyl alcohol by volume) the mean heart rate and rate-pressure product decreased significantly at the end of each stage of exercise compared to corresponding prealcohol values. There were also significant derangements in systolic time intervals parameters in the form of decrease in left ventricular ejection time I and increase in pre-ejection phase I and pre-ejection phase/left ventricular ejection time ratio after alcohol intake indicating a depression in left ventricular performance.

Developing a scale to measure hospital sales orientation.

The authors examine the sales orientation of the hospital and how it relates to the implementation of sales management policies. By polling sales managers and marketing directors at 136 hospitals nationwide, they develop scales to measure hospital sales orientation and sales management policies, and explore the relationship between them.

Dieulafoy's lesion: a rare cause of massive upper gastrointestinal haemorrhage.

Out of 900 cases of Upper Gastrointestinal haemorrhage seen during 1985-1989, 6 (0.67%) cases had Dieulafoy's lesion as the causative factor. All patients presented with massive upper gastrointestinal haemorrhage.