Publications by authors named "Aher K"
Article Synopsis
- Plaque psoriasis (PsO) is a chronic condition that requires long-term treatment, making drug persistence crucial for ongoing effectiveness and patient tolerance.
- This study analyzed treatment persistence and discontinuation rates of various biologic agents and apremilast among PsO patients in Finland and Sweden, focusing on data from 2008-2020.
- Results showed that guselkumab and ustekinumab had the highest persistence rates, with 90% and 85% of patients continuing treatment for at least one year, and guselkumab had lower discontinuation rates compared to other treatments.
Glioblastoma (GBM) is a highly aggressive and lethal type of brain tumor with complex and diverse molecular signaling pathways involved that are in its development and progression. Despite numerous attempts to develop effective treatments, the survival rate remains low. Therefore, understanding the molecular mechanisms of these pathways can aid in the development of targeted therapies for the treatment of glioblastoma.
View Article and Find Full Text PDFBreast cancer invasive 2.3 million women worldly and second prominent factor of cancer-related mortality. Finding a new site-specific and safe small molecule is a current need in this field.
View Article and Find Full Text PDFSimple, sensitive, precise, and specific high-performance liquid chromategraphic (HPLC) and high-performance thin-layer chromatographic (HPTLC) methods for the determination of dolutegravir sodium in bulk drug and pharmaceutical dosage form were developed and validated. In the HPLC method, analysis of the drug was carried out on the ODS C18 column (150 × 4.6 mm, 5 μm particle size) using a mixture of acetonitrile: water (pH 7.
View Article and Find Full Text PDFAim: A simple, rapid, precise, and economical spectrophotometric method has been developed for quantitative analysis of zaltoprofen (ZLT) in pharmaceutical formulations.
Materials And Methods: A mixture of methanol and water was used as a solvent. Initial stock solution of ZLT was prepared in methanol and subsequent dilution was done in water.