Improved chromatographic performance in red chilli powder pesticide residue quantitation by retention gap introduction in gas chromatography tandem mass spectrometry.

Unlabelled: Analysis of agrochemical residues in red chilli powder is always considered difficult because of higher matrix interference due to carotenoid pigments and other co-extractives. During the sample preparation, matrix components were co-extracted along with the target compounds leading to frequent source cleaning, changing of liner and column. Efforts were made to improve the chromatographic performance by optimizing sample preparation, choosing matrix-free transitions and introducing a retention gap.

Comparative evaluation of multi-residue methods for analysis of pesticide residues in black pepper by gas chromatography tandem mass spectrometry: critical evaluation of matrix co-extractives and method validation.

A gas chromatography tandem mass spectrometry method was developed for simultaneous determination of 133 pesticides in Black pepper (). QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) sample preparation method is preferred over multistep methods. Extraction was done by using acetonitrile followed by clean up using graphitized carbon, primary secondary amine and octadecyl silica (C).