Orthokeratinized Odontogenic Cyst in the Posterior Maxilla and Its Surgical Management: A Report of a Rare Case.

Orthokeratinized odontogenic cyst (OOC) is a rare developmental anomaly of the jaw, now formally recognized as a distinct entity due to its unique biological characteristics, specialized histopathological features, reduced aggressiveness, and significantly lower recurrence rate compared to odontogenic keratocysts. This report describes a case in which the cyst was surgically enucleated, and a comprehensive histopathological evaluation of the specimen confirmed the diagnosis of OOC. The report provides an in-depth exploration of the clinical management and therapeutic strategies employed in addressing this atypical and clinically significant pathological condition.

Unveiling the pH-Responsive Mechanisms of the Carbon Dot-Proximicin-A Peptide Conjugate for Targeted Cancer Therapy Using Density Functional Theory.

This study investigates the pH-responsive dissociation mechanism of carbon dot (CD) conjugated with the anticancer peptide proximicin-A (PROXI) using density functional theory (DFT) simulations. The CD@PROXI system, designed for targeted cancer therapy, releases the drug in acidic environments typical of cancer sites. DFT simulations, with the B3LYP-D3BJ functional and 6-311G (d, p) basis set, optimized the conjugate's geometry under neutral and acidic conditions.

Microscopic Characterization Based Synthesis of Silver Nanoparticles Using Merremia quinquefolia (L.) Hallier f. Leaf Extract: Their Biological Approaches and Degradation of Methylene Blue Dye.

The green methods for the synthesis of silver nanoparticles (AgNPs) has developed popularity recently due to the low preparation costs, environmental friendliness, and non-toxicity of the precursors. In this study, AgNPs were synthesized using leaf extract from Merremia quinquefolia. Spectroscopic techniques were used for analyzing the functional groups, morphology, crystalline phase, and elemental composition of nanomaterials.

Synthesis of chitosan and carboxymethyl cellulose connect flavonoid (CH-Fla-CMC) composite and their investigation of antioxidant, cytotoxicity activities.

This study successfully synthesised and characterised composites combining chitosan (CH), carboxymethyl cellulose (CMC), and various flavonoids (Fla). This innovative approach demonstrates the potential for developing functional materials with antioxidant and food preservation properties. The composites CH-Fla-CMC (1-5) was characterised using advanced techniques such as FT-IR, UV-Vis, XRD, SEM, TEM, and TGA, providing robust data on their structural, morphological, and thermal properties.

Theoretical Study of CO, NO, NO, Cl, and HS Adsorption Interactions with PdO-Graphene Composites for Gas Sensor Applications.

Gas sensors play a vital role in detecting gases in the air, converting their concentrations into electrical signals for industrial, environmental, and safety applications. This study used density functional theory methods to explore the mechanism and sensitivity of a PdO-graphene composite sensor towards various gases (CO, NO, NO, HS, and Cl). All calculations, including structure, energy, and frequency optimizations, were performed using the Gaussian software with appropriate configurations and basis sets.

Cu(II)-Catalyzed Synthesis of Pyrazolo[3,4-]pyridine Derivatives and Their Potential Antibacterial and Cytotoxic Activities with Molecular Docking, DFT Calculation, and SwissADME Analysis.

The present work focuses on a newly synthesized pyrazolo[3,4-]pyridine prepared by formal [3 + 3] cycloaddition using copper(II) acetylacetonate as the catalyst; efficient and effective mild reactions with high yields were obtained using this method. The synthesized compounds were identified by FT-IR, H and C NMR, and mass spectra (/) analyses. The compounds () were screened for several in vitro and in silico activities.

Anti-Bacterial and Anti-Dermatophytic Activity of Extracellular Secondary Metabolites of Streptomyces glaucescens NTSB-37 Isolated from Lichen Parmotrema perlatum (Huds.) M. Choisy in Kolli Hills, Tamil Nadu, India.

Lichen-associated endophytic Actinobacteria, particularly Streptomyces species, are recognized for their production of bioactive secondary metabolites with significant pharmaceutical potential. With the escalating prevalence of diseases, Streptomyces species are being investigated for its natural source of antimicrobial compounds for new antibiotics. This study focuses on the bioactive properties of secondary metabolites from lichen-associated endophytic Actinobacteria, focusing on Streptomyces glaucescens NTSB-37 isolated form lichen, Parmotrema perlatum (Huds.

Algae-mediated copper nanocatalyst for aerobic oxidation and dye decolourization via sustainable wastewater treatment.

In recent years, several physicochemical methods have been proposed for decolourising textile dyes; however, few have been adopted by the textile industry because of factors such as high cost, low efficiency, and limited applicability to a wide range of dyes. The current study focuses on synthesising algae-mediated Cu and CuO nanocatalysts (Alg-Cu and Alg-CuO) using natural waste materials from green algae. The synthesised Alg-CuO nanocatalyst was characterised and confirmed using SEM, TEM, UV, FT-IR, XRD, XPS, GC-MS, and TGA.

Synthesis, antimicrobial, antioxidant, tyrosinase inhibitory activities, and computational studies of novel chromen[2,3-c]pyrazole derivatives.

In this study, one-pot multicomponent reactions of novel chromeno[2,3-c]pyrazole derivatives (1-14) were performed using an AlCl catalyst via cyclisation. Various spectral and chromatographic techniques were used to elucidate the structure of the synthesised derivatives (1-14). The synthesised compounds were then inspected for their antibacterial, antioxidant, and tyrosinase inhibition activities.

The European Nucleotide Archive in 2024.

The European Nucleotide Archive (ENA, https://www.ebi.ac.

The Influence of Glycemic Control Over Post-extraction Healing in Diabetic Patients.

Background Diabetes mellitus hinders wound healing after tooth extractions due to hyperglycemia, causing complications like infections and delayed recovery. The precise role of glycemic control in healing remains uncertain. This study aims to clarify it by comparing outcomes in patients with well-controlled and poorly controlled blood sugar levels.

Synthesis of omega-3 mediated copper (ω-3-Cu) and copper oxide (ω-3-CuO) nanocatalyst dual application of dye decolourization and aerobic oxidation of eco-friendly sustainable approach.

In this study, ω-3-Cu and ω-3-CuO nanocatalysts were investigated for industrial environmental issues. Nowadays, green methodology is very important for addressing industrial environmental issues. In this regard, the current study focuses on ω-3-Cu and ω-3-CuO used for aerobic oxidation and dye decolourization via an eco-friendly approach.

Cu(II)-tyrosinase enzyme catalyst mediated synthesis of mosquito larvicidal active pyrazolidine-3,5-dione derivatives with molecular docking studies and their ichthyotoxicity analysis.

The objective of this study was to develop pyrazolidine-3,5-dione derivatives with potential as environmentally friendly pesticides for pest control, specifically focusing on their efficacy as larvicidal agents. A novel one-pot synthesis of multicomponent pyrazolidine-3,5-dione derivatives (1a-m) was accomplished via the grindstone method using Cu(II)tyrosinase enzyme as a catalyst under mild reaction conditions, yielding 84%-96%. The synthesised derivatives (1a-m) were characterized using various spectroscopic methods (mass spectrometry, elemental analysis, FT-IR, and 1H and 13C NMR).

Electrothermally-Driven Ultrafast Chemical Modulation of Multifunctional Nanocarbon Aerogels.

Ultrahigh-temperature Joule-heating of carbon nanostructures opens up unique opportunities for property enhancements and expanded applications. This study employs rapid electrical Joule-heating at ultrahigh temperatures (up to 3000 K within 60 s) to induce a transformation in nanocarbon aerogels, resulting in highly graphitic structures. These aerogels function as versatile platforms for synthesizing customizable metal oxide nanoparticles while significantly reducing carbon emissions compared to conventional furnace heating methods.

An Optimization Tool to Formulate Diets within a Supplementary Nutrition Program for Children.

Background: In large supplementary feeding programs for children, it is challenging to create and sustain contextual, acceptable, nutritionally complete, and diverse supplemental foods. For example, the Indian Supplementary Nutrition Program (SNP) supplements the dietary intake of children, pregnant and lactating women, and severely acutely malnourished (SAM) children by offering dry take home rations (THRs) or hot cooked meals (HCMs) across India, but an optimization tool is necessary to create local contextual recipes for acceptable and nutritionally adequate products.

Objectives: This study aimed to create a linear programming (LP) model to optimize diverse food provisions for a SNP to meet its program guidelines, using locally available foods, within budgetary allocations.

A Julolidine Aldehyde Dansyl Hydrazine Schiff Base as Fluorescence Chemosensor for Zn ions Recognition and its Application.

The Schiff base fluorescent probe (Dz-Jul), containing julolidine aldehyde and dansyl hydrazine, was derived using a simple condensation. This chemosensor showed high selectivity towards Zn and quick response (170 s) in DMSO/HO solutions (8/2, v/v, pH 7.2 buffer).

Assessment of growth, reproduction, and vermi-remediation potentials of Eisenia fetida on heavy metal exposure.

Heavy metal pollution is a significant environmental concern with detrimental effects on ecosystems and human health, and traditional remediation methods may be costly, energy-intensive, or have limited effectiveness. The current study aims were to investigate the impact of heavy metal toxicity in Eisenia fetida, the growth, reproductive outcomes, and their role in soil remediation. Various concentrations (ranging from 0 to 640 mg per kg of soil) of each heavy metal were incorporated into artificially prepared soil, and vermi-remediation was conducted over a period of 60 days.

Unique Hyperspectral Response Design Enabled by Periodic Surface Textures in Photodiodes.

The applications of hyperspectral imaging across disciplines such as healthcare, automobiles, forensics, and astronomy are constrained by the requirement for intricate filters and dispersion lenses. By utilization of devices with engineered spectral responses and advanced signal processing techniques, the spectral imaging process can be made more approachable across various fields. We propose a spectral response design method employing photon-trapping surface textures (PTSTs), which eliminates the necessity for external diffraction optics and facilitates system miniaturization.

Comparative Evaluation of Antibacterial Efficacy, Molecular Docking of Ethanolic Extract of Blackseed, Seaweed and Calcium Hydroxide Intracanal Medicament with Enterococcus Faecalis Antigens.

Aim: To evaluate the inhibitory effect of ethanolic extract blackseed, seaweed, and calcium hydroxide intracanal medicament with Enterococcus faecalis biofilm. To study the binding interaction between the active components of blackseed and seaweed against the enterococcal surface protein of () by molecular docking.

Materials And Methods: The ethanolic extracts of blackseed and seaweed were prepared using the Soxhlet apparatus.

Comparative Evaluation of Volume and Homogeneity of Obturation with Four Different Obturation Systems Using Micro-Computed Tomography: An Study.

Aim: To evaluate and compare volume and homogeneity of the three different root canal obturation systems.

Materials And Methods: Single-rooted premolar (n = 24) teeth samples were selected, and crowns were removed for standardization. Four groups are divided randomly as (n = 6), namely: For group I (single-cone gutta-percha obturation), group II (Beefill 2 in 1 obturation), group III (GuttaCore obturation), group IV (GuttaFlow bioseal obturation) and the root canal were subjected to prepare till X3 (protaper next) and subjected to micro-CT imaging.

Unveiling the mysteries: Functional insights into hypothetical proteins from 638R.

Humans benefit from a vast community of microorganisms in their gastrointestinal tract, known as the gut microbiota, numbering in the tens of trillions. An imbalance in the gut microbiota known as dysbiosis, can lead to changes in the metabolite profile, elevating the levels of toxins like toxin (BFT), colibactin, and cytolethal distending toxin. These toxins are implicated in the process of oncogenesis.

Functional characterization of Malabar grouper (Epinephelus malabaricus) interferon regulatory factor 9 involved in antiviral response.

IRF9 is a crucial component in the JAK-STAT pathway. IRF9 interacts with STAT1 and STAT2 to form IFN-I-stimulated gene factor 3 (ISGF3) in response to type I IFN stimulation, which promotes ISG transcription. However, the mechanism by which IFN signaling regulates Malabar grouper (Epinephelus malabaricus) IRF9 is still elusive.

Synthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking.

Purpose: New bioactive anthraquinone derivatives are investigated for antibacterial, tyrosinase inhibitory, antioxidant cytotoxic activity, and molecular docking.

Methods: The compounds were produced using the grindstone method, yielding 69 to 89%. These compounds were analyzed using IR, H, and C NMR and elemental and mass spectral methods.