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View Article and Find Full Text PDFGlaucoma is the most prevalent neurodegenerative disease and a leading cause of blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not fully understood. Here we show, using mice deficient in T and/or B cells and adoptive cell transfer, that transient elevation of intraocular pressure (IOP) is sufficient to induce T-cell infiltration into the retina.
View Article and Find Full Text PDFIntroduction Ophthalmic segment aneurysms may present with visual symptoms due to direct compression of the optic nerve. Treatment of these aneurysms with the Pipeline embolization device (PED) often results in visual improvement. Flow diversion, however, has also been associated with occlusion of the ophthalmic artery and visual deficits in a small subset of cases.
View Article and Find Full Text PDFPurpose: Choroidal metastasis from bladder cancer is very rare, with only a handful of cases cited previously in the literature. We present a case of a patient who presented with a serous retinal detachment and a known history of bladder cancer, which he believed was controlled. Based on the clinical evaluation, his history of bladder cancer, and a retinal consult, a workup was initiated and he was found to have choroidal metastasis from his cancer.
View Article and Find Full Text PDFWe present a case of diabetic macular edema in a pregnant patient treated with a single intravitreal injection of triamcinolone acetonomide. Initial presentation and serial examinations after treatment included visual acuity, slit-lamp examination, indirect ophthalmoscopy, and optical coherence tomography. Resolution of visual acuity and macular edema were present six weeks after injection and persisted throughout the duration of the pregnancy without further intervention.
View Article and Find Full Text PDFPurpose: The goal of this study was to review, evaluate, and perform a meta-analysis on the current literature that reports rates of postoperative endophthalmitis after small gauge transconjunctival sutureless vitrectomy (TSV) and compare it to 20-gauge pars plana vitrectomy (20G PPV).
Methods: We performed an extensive review of the current literature. We included only large comparative institutional reviews.
Ophthalmic Surg Lasers Imaging
September 2009
A 29-year-old woman with membranoproliferative glomerulonephritis type II presented with decreased vision due to choroidal neovascular membrane. She was treated with monthly intravitreal injections of bevacizumab. Although there was dramatic improvement in her vision after the third injection, it continued to improve through the ninth monthly injection.
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