Publications by authors named "Ahad Ashrafi-Asgarabad"
One of the most frequent environmental contaminants, benzene is still widely used as an industrial solvent around the world, especially in developing nations, posing a serious occupational risk. While the processes behind the toxicity of benzene grounds are not fully understood, it is generally accepted that its metabolism, which involves one or more reactive metabolites, is crucial to its toxicity. In order to evaluate the many ways that benzene could influence gene regulation and thus have an impact on human health, new methodologies have been created.
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- Exposure to air pollution leads to around seven million premature deaths and significantly contributes to disability, with particulate matter (PM) being a primary pollutant.
- PM2.5, due to its large surface area, can absorb harmful substances and cause cellular issues like oxidative stress, inflammation, and apoptosis.
- Non-coding RNAs (ncRNAs) are increasingly recognized for their role in responding to environmental changes, with exposure to PM2.5 linked to alterations in these ncRNAs, impacting health and disease processes.
Background: Lower respiratory infections (LRIs) cause substantial mortality and morbidity. The present study reported and analysed the burden of LRIs in the Middle East and North Africa (MENA) region between 1990 and 2019, by age, sex, etiology, and socio-demographic index (SDI).
Methods: The data used in this study were sourced from the Global Burden of Disease (GBD) study 2019.
Introduction: Understanding trends in the annual incidence, mortality, and disability-adjusted life-years (DALYs) for tracheal, bronchus, and lung (TBL) cancer globally is important to enable appropriate targeting of resources for prevention, clinical practice improvement, and research. The aim of this study was to determine the global, regional, and national burdens of TBL cancer in 204 countries and territories from 1990 to 2019 by age, sex, and sociodemographic index.
Methods: Estimates were produced through various data inputs including the following: cancer registries (n = 5318), vital registration (n = 22,553), vital registration-sample (n = 825), and verbal autopsies (n = 516).
Article Synopsis
- The study aims to analyze the prevalence, deaths, and disability-adjusted life years (DALYs) related to musculoskeletal disorders, including low back pain, neck pain, and arthritis, from 1990 to 2017 across 195 countries.
- Data was collected using the Global Burden of Disease Study 2017, and results were estimated using advanced statistical methods to report rates per 100,000 people.
- In 2017, approximately 1.3 billion cases of musculoskeletal disorders were found globally, with low back pain being the most common type, while both prevalence and DALYs slightly decreased from 1990, particularly affecting women and older age groups.
Objectives: To describe the level and trends of point prevalence, deaths and disability-adjusted life years (DALYs) for other musculoskeletal (MSK) disorders, i.e. those not covered by specific estimates generated for RA, OA, low back pain, neck pain and gout, from 1990 to 2017 by age, sex and sociodemographic index.
View Article and Find Full Text PDFKidney cancer globally accounts for more than 131,000 deaths each year and has been found to place a large economic burden on society. However, there are no recent articles on the burden of kidney cancer across the world. The aim of this study was to present a status report on the incidence, mortality and disability-adjusted life years (DALYs) associated with kidney cancer in 195 countries, from 1990 to 2017.
View Article and Find Full Text PDFPrevalence, Incidence, and Years Lived With Disability Due to Gout and Its Attributable Risk Factors for 195 Countries and Territories 1990-2017: A Systematic Analysis of the Global Burden of Disease Study 2017.
Arthritis Rheumatol
November 2020
Article Synopsis
- The objective of the study was to analyze the prevalence, incidence, and years lived with disability (YLD) due to gout across 195 countries from 1990 to 2017, factoring in age, sex, and sociodemographic indices.
- Data was derived from the Global Burden of Disease 2017 study, using systematic reviews and disease modeling to provide comprehensive estimates at global, regional, and national levels.
- The findings revealed approximately 41.2 million cases of gout worldwide in 2017, with an increase in both prevalence and incidence since 1990, particularly in older males, and a higher burden in developed countries.
Objectives: To report the level and trends of prevalence, incidence and years lived with disability (YLDs) for osteoarthritis (OA) in 195 countries and territories from 1990 to 2017 by age, sex and Socio-demographic index (SDI; a composite of sociodemographic factors).
Methods: Publicly available modelled data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 were used. The burden of OA was estimated for 195 countries and territories from 1990 to 2017, through a systematic analysis of prevalence and incidence modelled data using the methods reported in the GBD 2017 Study.
Objective: To use data from the Global Burden of Disease Study between 1990 and 2017 to report the rates and trends of point prevalence, annual incidence, and years lived with disability for neck pain in the general population of 195 countries.
Design: Systematic analysis.
Data Source: Global Burden of Diseases, Injuries, and Risk Factors Study 2017.
Objectives: To perform a meta-analysis on the relationship type 2 diabetes has with serum hepcidin and the hepcidin/ferritin ratio.
Methods: The following databases were searched using all relevant keywords: Web of Science, Medline, Scopus, Embase and Google Scholar. All studies that examined the relationship type 2 diabetes has with serum hepcidin or the hepcidin/ferritin ratio were included in this meta-analysis and systematic review provided, were published in English between 2011 and 2018.
Objectives: To provide the level and trends of prevalence, incidence and disability adjusted life years (DALYs) for rheumatoid arthritis (RA) in 195 countries from 1990 to 2017 by age, sex, Socio-demographic Index (SDI; a composite of sociodemographic factors) and Healthcare Access and Quality (an indicator of health system performance) Index.
Methods: Data from the Global Burden of Diseases, Injuries, and Risk Factors study (GBD) 2017 were used. GBD 2017 modelled the burden of RA for 195 countries from 1990 to 2017, through a systematic analysis of mortality and morbidity data to estimate prevalence, incidence and DALYs.
Background: Mental health is one of the characteristic benchmarks of public health. This research aimed to evaluate mental health of survivors of the Bam earthquake which occurred in 2003 twelve years after the earthquake in fall of 2015.
Methods: The statistical population of this cross-sectional study were people over 16 years of age who were present at the time of the earthquake in the city of Bam.