Publications by authors named "Ah Leum Kim"

Background: Accurate estimation of cell viability is crucial in various applications such as cytotoxicity testing and routine cell culture on both industrial and laboratory scales. For this, the real-time monitoring of cell status would be beneficial. Conventional cell-based assays for cell viability have limitations in sensitivity and time-effectiveness.

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Article Synopsis
  • Quantitative PCR (qPCR) is a key method for detecting specific nucleic acid sequences related to pathogens, including SARS-CoV-2, but can be affected by issues like heterodimer formation.
  • This study explores optimizing multiplex qPCR and digital PCR (dPCR) for better detection of COVID-19, highlighting that dPCR is more resilient to suboptimal conditions and less affected by heterodimers.
  • By improving primer sequences in the RdRp assay and correcting cycling conditions, dPCR not only enhances sensitivity and accuracy but also has the potential to lower costs and time in SARS-CoV-2 diagnostics.
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spp. constitute a significant global threat as a leading cause of foodborne illnesses, with poultry meat as a prominent reservoir for these pathogens. South Korea is known for its diverse poultry consumption habits, and continuous outbreaks make it a matter of concern to perform a meta-analysis to identify the primary source of contamination.

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Preeclampsia is a common disease that can occur during human pregnancy and is a leading cause of both maternal and neonatal morbidity and mortality. Inadequate trophoblast invasion and deficient remodeling of uterine spiral arteries are associated with preeclampsia (PE). The development of this syndrome is thought to be related to multiple factors.

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