Publications by authors named "Aguyda Rayany Cavalcante Barbosa"
The environment preservation has been an important motivation to find alternative, functional, and biodegradable materials to replace polluting petrochemicals. The production of nonbiodegradable face masks increased the concentration of microplastics in the environment, highlighting the need for sustainable alternatives, such as the use of local by-products to create efficient and eco-friendly filtering materials. Furthermore, the use of smart materials can reduce the risk of contagion and virus transmission, especially in the face of possible mutations.
View Article and Find Full Text PDFHybrid Immunity Results in Enhanced and More Sustained Antibody Responses after the Second Sinovac-CoronaVac Dose in a Brazilian Cohort: DETECTCoV-19 Cohort.
Viruses
September 2023
We measured anti-SARS-CoV-2 antibody responses before and after CoronaVac (inactivated) vaccination in a case-control study performed in CoronaVac-immunized individuals participating in a longitudinal prospective study of adults in Manaus (DETECTCoV-19). Antibody responses were measured by standard serological immunoassays. Peak anti-S-RBD and neutralizing RBD-ACE2 blocking antibody responses after two doses of CoronaVac vaccine were similar in vaccine breakthrough cases ( = 9) and matched controls ( = 45).
View Article and Find Full Text PDFHigh anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort.
Lancet Glob Health
November 2021
Article Synopsis
- The study examines anti-SARS-CoV-2 nucleocapsid IgG antibody seroconversion rates among adult residents of Manaus, Brazil, amid the COVID-19 pandemic, specifically focusing on data before the second wave of cases.
- A convenience sample was taken from the DETECTCoV-19 study cohort, involving participants with two serum sample collections and strict eligibility criteria regarding prior COVID-19 diagnoses.
- Results indicated that out of 2,496 participants returning for follow-up, 559 were initially seropositive, and analyses were conducted to determine correlations between seroconversion and various sociodemographic and health-related factors.
Article Synopsis
- Host genetics play a crucial role in determining an individual's resistance or susceptibility to active pulmonary tuberculosis (TB).
- A specific genetic variant, rs10818488 in the TRAF1/C5 gene, is linked to a higher risk of developing TB, with a significant association found in multibacillary cases leading to increased bacterial load in the lungs.
- The study indicates that a "loss-of-function" variant in TRAF1/C5 may lower the production of TNF-α, thereby increasing susceptibility to TB and affecting the clinical severity of the disease.
SARS-CoV-2 seroprevalence and associated factors in Manaus, Brazil: baseline results from the DETECTCoV-19 cohort study.
Int J Infect Dis
September 2021
Background: Manaus, located in the Brazilian rainforest, has experienced two health system collapses due to the coronavirus disease 2019 (COVID-19) pandemic. However, little is known about which groups among the general population have been most affected.
Methods: A convenience sampling strategy via online advertising recruited 3046 adults between 19 August 2020 and 2 October 2020.