Reversible dioxygen uptake at [Cu] clusters.

Dioxygen binding solely through non-covalent interactions is rare. In living systems, dioxygen transport takes place iron or copper-containing biological cofactors. Specifically, a reversible covalent interaction is established when O binds to the mono or polynuclear metal center.

Learnings from the Relation between the Number of Forward and Reverse Reactions (Transfer Cycles) Required to Converge to Equilibrium and the Ratio of the Forward to the Reverse Rate Constants in Simple Chemical Reactions.

In simple, reversible, chemical reactions of the type A ⇋ B, chemical equilibrium is related to chemical kinetics via the equality between the equilibrium constant and the ratio of the forward to the reverse rate-constant, i.e., = / , where is the equilibrium constant and and denote the rate constants for the forward (A → B) and reverse (B → A) reactions, respectively.