Publications by authors named "Agustin Moreno"

Purpose: To describe the development, implementation, and evaluation of a pharmacy clinical decision support tool designed to increase naloxone coprescription among people at risk for opioid overdose in a large healthcare system.

Summary: The Military Health System Opioid Registry and underlying presentation layer were used to develop a clinical decision support capability to improve naloxone coprescription at the pharmacy point of care. Pharmacy personnel use a patient identification card barcode scanner or manually enter a patient's identification number to quickly visualize information on a patient's risk for opioid overdose and medical history related to pain and, when appropriate, receive a recommendation to coprescribe naloxone.

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Article Synopsis
  • Intravenous calcitriol effectively lowers parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism, but about half of the patients don't respond to the treatment.
  • The study involved 60 hemodialysis patients who received initial calcitriol therapy followed by imaging with technetium Tc 99m-sestamibi (MIBI) to evaluate their parathyroid glands before and after treatment.
  • Results showed that MIBI scintigraphy can help predict which patients are likely to respond to calcitriol, with significant decreases in iPTH levels observed after one year, particularly in those with fewer MIBI-positive areas.
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Background: Although bisphosphonates have been widely used to treat bone diseases characterized by increased bone resorption, there are limited data showing their possible usefulness in patients on hemodialysis (HD) with secondary hyperparathyroidism.

Methods: The aim of this study was to evaluate the efficacy and safety of pamidronate in HD patients affected by severe secondary hyperparathyroidism and moderate hypercalcemia who were receiving intravenous calcitriol (Calcijex).

Results: In this prospective one-year, open-labeled study, 13 patients (9 women/4 men) with a mean age of 64 +/- 9 years and a mean time on dialysis of 94 +/- 61 months were evaluated.

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